Evidence map›Paper›PMID 41324825›Full record

Observational studyClinical and experimental nephrology2026

Longitudinal change in thigh muscle cross-sectional area in association with hospitalization among patients undergoing hemodialysis: the Osaka Dialysis Complication Study (ODCS).

Shota Matsufuji, Tetsuo Shoji, Suhye Lee, Yoshihiro Tsujimoto, Shinya Nakatani, Tomoaki Morioka, Katsuhito Mori, Masanori Emoto

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Clinical and experimental nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shota MatsufujiDepartment of Metabolism, Endocrinology and Molecular Medicine, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Tetsuo ShojiDepartment of Metabolism, Endocrinology and Molecular Medicine, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan. tetsuoshoji@omu.ac.jp.ORCID http://orcid.org/0000-0003-3953-0925
Suhye LeeDivision of Rehabilitation, Inoue Hospital, Suita, Japan.
Yoshihiro TsujimotoDivision of Internal Medicine, Inoue Hospital, Suita, Japan.
Shinya NakataniDepartment of Nephrology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Tomoaki MoriokaDepartment of Metabolism, Endocrinology and Molecular Medicine, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Katsuhito MoriDepartment of Nephrology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Masanori EmotoDepartment of Metabolism, Endocrinology and Molecular Medicine, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients undergoing hemodialysis have decreased skeletal muscle mass which is associated with higher mortality and lower physical functioning. Since these patients frequently experience hospitalizations, we hypothesized that hospital admissions could be a cause of loss of skeletal muscle mass.

methodsThis was a longitudinal observational study among patients on hemodialysis (N = 132). The outcome was the change in thigh muscle cross-sectional area (TMCSA) measured by computed tomography and standardized by squared height (cm

resultsDuring a median follow-up period of 3.95 years, 104 patients were hospitalized (hospitalization group), whereas 28 patients were not (non-hospitalization group). Both groups showed a significant decrease in TMCSA, and it was more rapid in the hospitalization group than the non-hospitalization group (P = 0.023). Multivariable-adjusted linear regression analysis showed that the total number of hospital admissions and the total length of hospital stays were the independent factors associated with the decrease in TMCSA.

conclusionThis study showed for the first time that hospital admissions were independently associated with the longitudinal decrease in TMCSA in patients undergoing hemodialysis.

Indexed as

HospitalizationMuscle, SkeletalRenal DialysisSarcopeniaAgedFemaleHumansJapanLength of StayLongitudinal StudiesMaleMiddle AgedRisk FactorsThighTime FactorsTomography, X-Ray ComputedHemodialysisHospitalizationSkeletal muscle massThigh muscle cross-sectional area

Identifiers

PMID41324825

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.