Evidence map›Paper›PMID 41326174›Full record

ArticleLife science alliance2026

The unfolded protein response in progeria arteries originates from non-endothelial cell types.

Raquel A Silva, Fatih Sarigol, G Elif Karagöz, Selma Osmanagic-Myers, Roland Foisner

Abstract read
In one paragraph

Article in Life science alliance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Raquel A SilvaMax Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria.ORCID 0009-0002-4936-158X
Fatih SarigolMax Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria.ORCID 0000-0002-5842-6114
G Elif KaragözMax Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria.
Selma Osmanagic-MyersCenter for Pathobiochemistry and Genetics, Medical University of Vienna, Vienna, Austria selma.osmanagic-myers@meduniwien.ac.at.ORCID 0000-0002-3834-1332
Roland FoisnerMax Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria roland.foisner@meduniwien.ac.at.ORCID 0000-0003-4734-4647

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hutchinson-Gilford Progeria Syndrome (HGPS) is a premature aging disease caused by a mutation in

Indexed as

ArteriesProgeriaUnfolded Protein ResponseAnimalsAortaDisease Models, AnimalEndoplasmic Reticulum StressEndothelial CellsFibroblastsHumansLamin Type AMaleMiceMuscle, Smooth, VascularLamin Type ALmna protein, mouseprelamin A

Identifiers

PMID41326174
PMCPMC12670121

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.