Evidence map›Paper›PMID 41326556›Full record

ArticleScientific reports2025

Relationship between age-related hearing loss and alcohol consumption in a Japanese population.

Hiyori Takahashi, Jun Suzuki, Ikuko N Motoike, Miyuki Sakurai, Yuta Kobayashi, Gosuke Watarai, Hiroki Tozuka, Mana Kogure, Tetsuaki Kawase, Yohei Honkura and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Hiyori TakahashiDepartment of Otolaryngology, Head and Neck Surgery, Tohoku University School of Medicine, 1-1 Seiryo-machi, Aoba-Ku, Sendai, 980-8574, Japan.
Jun SuzukiDepartment of Otolaryngology, Head and Neck Surgery, Tohoku University School of Medicine, 1-1 Seiryo-machi, Aoba-Ku, Sendai, 980-8574, Japan. jun.suzuki.c2@tohoku.ac.jp.
Ikuko N MotoikeTohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan.
Miyuki SakuraiTohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan.
Yuta KobayashiDepartment of Otolaryngology-Head and Neck Surgery, JCHO Sendai Hospital, Sendai, Miyagi, Japan.
Gosuke WataraiDepartment of Otolaryngology, Head and Neck Surgery, Tohoku University School of Medicine, 1-1 Seiryo-machi, Aoba-Ku, Sendai, 980-8574, Japan.
Hiroki TozukaDepartment of Otolaryngology, Head and Neck Surgery, Tohoku University School of Medicine, 1-1 Seiryo-machi, Aoba-Ku, Sendai, 980-8574, Japan.
Mana KogureTohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan.
Tetsuaki KawaseDepartment of Otolaryngology, Head and Neck Surgery, Tohoku University School of Medicine, 1-1 Seiryo-machi, Aoba-Ku, Sendai, 980-8574, Japan.
Yohei HonkuraDepartment of Otolaryngology, Head and Neck Surgery, Tohoku University School of Medicine, 1-1 Seiryo-machi, Aoba-Ku, Sendai, 980-8574, Japan.
Ryoukichi IkedaDepartment of Otolaryngology, Head and Neck Surgery, Iwate Medical University School of Medicine, 19-1 Odori, Yahaba, Shiwa, Japan.
Kengo KinoshitaTohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan.
Naoki NakayaTohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan.
Taku ObaraTohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan.
Atsushi HozawaTohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan.
Shinichi KuriyamaTohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan.
Nobuo FuseTohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan.
Masayuki YamamotoTohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan.
Yukio KatoriDepartment of Otolaryngology, Head and Neck Surgery, Tohoku University School of Medicine, 1-1 Seiryo-machi, Aoba-Ku, Sendai, 980-8574, Japan.

Funding

JSPS KAKENHI JP23KK0156
6 · The paper itself

Abstract

Age-related hearing loss (ARHL) has a multifactorial pathogenesis, and the influence of alcohol consumption on it is controversial. This cross-sectional study investigated the association between ARHL and alcohol consumption by using cohort data from Tohoku Medical Megabank Project, including self-reported questionnaires and pure-tone audiometry thresholds (500, 1000, 2000, and 4000 Hz). ARHL was defined as a threshold of > 25 dB in the better ear. Multiple logistic regression analyses (age 50-79 y; 5,219 men and 9,266 women) were conducted separately for men and women and indicated that daily alcohol consumption levels of 60-80 and ≥ 80 g were significantly associated with increased odds of ARHL at 4,000 Hz in men (odds ratio [OR] 1.42; 95% confidence interval [CI] 1.05-1.94; OR 1.55; 95% CI 1.12-2.16; respectively); consumption of 10-20 g was significantly associated with reduced odds of ARHL at 4,000 Hz in women (OR 0.81; 95% CI 0.68-0.96). Assessment of drinking-related single nucleotide polymorphisms suggested that the effect of alcohol on ARHL may differ by genotype. Our findings suggest a sex-specific association between alcohol consumption and ARHL; heavy drinking is a potential risk factor in men, whereas moderate drinking may have a protective effect in women.

Indexed as

Alcohol DrinkingHearing LossPresbycusisAgedAudiometry, Pure-ToneCross-Sectional StudiesEast Asian PeopleFemaleHumansJapanMaleMiddle AgedPolymorphism, Single NucleotideRisk FactorsSurveys and QuestionnairesAge-related hearing lossAlcoholJapaneseSex differenceSingle nucleotide polymorphisms (SNPs)

Identifiers

PMID41326556
PMCPMC12770320

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.