Trial reportEuropean journal of clinical nutrition2026
A combined MeDi-DASH-CHH dietary intervention improves lipid profiles and enhances dietary adherence in northern Chinese older adults with dyslipidemia: A randomized controlled trial.
Trial report in European journal of clinical nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
11 authors.
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Abstract
backgroundDietary patterns targeting cardiometabolic health, such as the Mediterranean diet, DASH diet, and the Chinese Healthy Heart (CHH) dietary pattern have demonstrated lipid-lowering effects, yet culturally adapted strategies for older adults in northern China remain understudied. This study developed a combined MeDi-DASH-CHH dietary pattern by integrating key components of Western evidence-based diets (Mediterranean and DASH) with local dietary preferences (e.g., whole grain consumption, seasonal vegetable intake) to evaluate its impact on blood lipid control in northern Chinese older adults with dyslipidemia.
methodsA total of 210 dyslipidemic adults aged 60-75 years were stratified by sex, then randomized (1:1) to a 6-month intervention group (MeDi-DASH-CHH diet, with emphasized intake of aquatic products, dairy, and whole grains) or a control group (conventional guidance per Dietary Guidelines for Chinese Residents (2024)). Both groups received monthly follow-up visits. The primary outcome was the changes from baseline to six months in lipoprotein cholesterol (LDL-C). Secondary outcomes included changes in total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), dietary intake, and body composition indicators.
resultsAfter intervention, the intervention group showed improvements in lipid profiles compared to the control group (all P < 0.05). Dietary intake indicated increased consumption of whole grains, potatoes, vegetables, fruits, aquatic products, dairy products, and nuts, alongside reduced intake of livestock meat, poultry meat, and egg intake.
conclusionThe combined MeDi-DASH-CHH dietary effectively improves lipid profiles and promotes healthier eating behaviors in older adults with dyslipidemia in northern China.
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