Evidence map›Paper›PMID 41327349›Full record

ArticleHuman genomics2025

Genome-wide association study of lung function decline using elastic-net regression: a prospective analysis in Korean cohort.

Eunhye Bae, Sohee Oh, Jung-Kyu Lee, Eun Young Heo, Deog Kyeom Kim, Hyun Woo Lee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Human genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eunhye Bae *Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Chung-Ang University Gwangmyeong Hospital, Gwangmyeong-si, Republic of Korea.
Sohee Oh *Medical Research Collaborating Center, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of Korea.
Jung-Kyu LeeDivision of Pulmonary and Critical Care, Department of Internal Medicine, Seoul National University College of Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of Korea.
Eun Young HeoDivision of Pulmonary and Critical Care, Department of Internal Medicine, Seoul National University College of Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of Korea.
Deog Kyeom KimDivision of Pulmonary and Critical Care, Department of Internal Medicine, Seoul National University College of Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of Korea.
Hyun Woo LeeDivision of Pulmonary and Critical Care, Department of Internal Medicine, Seoul National University College of Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of Korea. athrunzara86@snu.ac.kr.

Funding

Seoul Metropolitan Government Seoul National University (SMG-SNU) Boramae Medical Center 04-2022-0015
6 · The paper itself

Abstract

backgroundA rapid decline in forced expiratory volume in one second (FEV

methodsWe conducted a genome-wide association study (GWAS) within the prospective Korean Genome and Epidemiology Study (KoGES) cohort. The association of each SNP with the annual decline rate of FEV

resultsIn 7,357 participants, we identified 21 SNPs associated with rapid FEV

conclusionOur study identified novel SNPs associated with FEV

Indexed as

Genome-Wide Association StudyLungPolymorphism, Single NucleotideAdultAgedCohort StudiesEast Asian PeopleFemaleForced Expiratory VolumeGenetic Predisposition to DiseaseHumansMaleMiddle AgedProspective StudiesRepublic of KoreaRisk FactorsGenetic risk scoreGenome-Wide association studyPolymorphismRegression analysisSingle nucleotideSpirometry

Identifiers

PMID41327349
PMCPMC12771834

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.