ReviewCureus2025
Factors Influencing the Predictability and Success of Invisalign Aligners: A Systematic Review.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- A 3D comparison of planned versus achieved anterior tooth position in clear aligner treatment.Scientific reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Invisalign clear aligners have become an increasingly popular alternative to fixed orthodontic appliances due to their esthetic appeal and comfort; however, their treatment outcomes remain variable across different patient groups and movement types. This systematic review aimed to evaluate clinical, biomechanical, and patient-related factors influencing the success and predictability of Invisalign treatment. Comprehensive searches were conducted in PubMed/MEDLINE, ScienceDirect, Google Scholar and the Cochrane Library for studies published up to August 2025. Eligible studies included randomized controlled trials, cohort, case-control, and cross-sectional designs assessing factors associated with Invisalign outcomes. Six studies met the inclusion criteria. The findings revealed that treatment success is multifactorial and primarily determined by patient compliance, treatment planning, and case complexity. Males and patients without prior orthodontic experience demonstrated higher compliance rates, while inadequate wear time was a major cause of suboptimal outcomes. Tooth movement predictability varied by type, with bucco-lingual tipping being most accurate, whereas rotation, intrusion, and expansion exhibited lower precision. Technological factors also played a role, as digital monitoring tools such as the Invisalign Progress Assessment were found to overestimate tooth movement. Compared with fixed appliances, Invisalign provided shorter treatment duration and improved comfort and esthetics, but less favorable results for certain smile parameters. Meta-analysis was not feasible due to heterogeneity in study design and outcome measures. Overall, the success of Invisalign therapy depends on a complex interaction of patient behavior, treatment planning, and technological precision. Further high-quality prospective studies are needed to standardize success criteria and refine predictive tools for improved treatment outcomes.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.