Evidence map›Paper›PMID 41328152›Full record

ArticleCureus2025

Asymmetrical Macular Thinning on Optical Coherence Tomography (OCT) in Pigmented Paravenous Retinochoroidal Atrophy.

Anaam Rahman, Anahita Jamil

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Anaam RahmanDepartment of Ophthalmology, Rawal Institute of Health Sciences, Islamabad, PAK.
Anahita JamilDepartment of Ophthalmology, Northwest General Hospital and Research Center, Peshawar, PAK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pigmented paravenous retinochoroidal atrophy (PPRCA) is a rare, typically non-progressive retinal disorder characterized by perivenous atrophy of the retinal pigment epithelium and choriocapillaris, with macular involvement being uncommon. This report aims to highlight a novel manifestation of asymmetrical macular thinning in PPRCA. A 40-year-old man presented with bilateral, gradual visual decline. Fundus examination revealed perivenous retinochoroidal atrophy with pigmentation along the arcades in both eyes and notable macular changes. Spectral-domain optical coherence tomography (OCT) demonstrated bilateral central retinal thinning, most marked in the temporal parafovea, with attenuation of both inner and outer retinal layers and preservation of the foveal depression. Fundus autofluorescence showed corresponding areas of hypoautofluorescence, while systemic evaluation excluded infectious and inflammatory causes. This case, to our knowledge, represents the first description of asymmetrical macular thinning in PPRCA, broadening the recognized spectrum of its macular involvement and emphasizing the diagnostic value of OCT in differentiating PPRCA from inflammatory and inherited retinal disorders.

Indexed as

fundus autofluorescencemacular thinningoptical coherence tomographypigmented paravenous retinochoroidal atrophyretinal dystrophy

Identifiers

PMID41328152
PMCPMC12664764

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.