ArticleHealth science reports2025
Interventions to Improve Medication Adherence in People With Hypertension: Protocol for a Systematic Review and Meta-Analysis.
Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Artificial Intelligence in Cardiovascular Medicine: Focus on Hypertension.Hypertension (Dallas, Tex. : 1979) · 2026Pooled it
- Interventions to Improve Medication Adherence in People With Hypertension: Protocol for a Systematic Review and Meta-Analysis.Health science reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Medication adherence is the extent to which a patient's behavior corresponds with the prescriber's recommendations for taking medications. Non-adherence is particularly high in patients with hypertension, leading to poor blood pressure control, increased cardiovascular risk, and increased burden on the healthcare system. A multitude of techniques and interventions to measure and improve medication adherence have been evaluated with mixed results. This protocol outlines a systematic review and meta-analysis of randomized controlled trials evaluating interventions aimed at improving medication adherence in people with hypertension. There will be a focus on investigating intervention impact on the duration of medication adherence, persistence, analysis of subjective versus objective medication adherence measurement techniques, the impact of patient demographics on intervention effectiveness, and the use of the Behavior Change Taxonomy to categorize behavior change interventions and facilitate their evaluation. Methods: This protocol was developed using the PRISMA-P checklist and prospectively registered in the International Prospective Register of Systematic Reviews (PROSPERO) (CRD42024614468). A comprehensive literature search was conducted using Medline (Ovid), CINAHL and Embase electronic databases for articles published from inception to November 27th, 2024. In addition, CENTRAL was searched for articles published up to the end of 2024. Fixed and/or random-effects meta-analysis will be used as appropriate, according to between study heterogeneity, and the risk of bias of included studies will be assessed using the Cochrane risk of bias tool. Results: The results and findings of this review will be reported in accordance with PRISMA guidelines and published in a peer-reviewed journal. Conclusion: The findings of this review will evaluate the evidence for interventions designed to improve medication adherence in people with hypertension. The results will provide evidence on which adherence interventions, or components of complex interventions, are effective and how they impact blood pressure control. Recommendations will be made for further research, including the design of interventions and methodology for medication adherence measurement.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.