Evidence map›Paper›PMID 41328348›Full record

ArticleTheranostics2026

Antibody-induced internalization and degradation of PLA2R amplifies CD4

Yuning Liu, Yinyin Li, Hui Zhou, Jieli Yu, Pei Deng, Weiwei Xu, Bingqian Pan, Lei Zhang, Hong Zhou, Jing Zhang and 7 more

Abstract read
In one paragraph

Article in Theranostics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Yuning LiuDivision of Nephrology, Nanfang Hospital, Southern Medical University; State Key Laboratory of Multi-organ Injury Prevention and Treatment; National Clinical Research Center for Kidney Disease; Guangdong Provincial Institute of Nephrology; Guangdong Provincial Key Laboratory of Renal Failure Research, Guangzhou, Guangdong 510515, China.
Yinyin LiDivision of Nephrology, Nanfang Hospital, Southern Medical University; State Key Laboratory of Multi-organ Injury Prevention and Treatment; National Clinical Research Center for Kidney Disease; Guangdong Provincial Institute of Nephrology; Guangdong Provincial Key Laboratory of Renal Failure Research, Guangzhou, Guangdong 510515, China.
Hui ZhouDivision of Nephrology, Nanfang Hospital, Southern Medical University; State Key Laboratory of Multi-organ Injury Prevention and Treatment; National Clinical Research Center for Kidney Disease; Guangdong Provincial Institute of Nephrology; Guangdong Provincial Key Laboratory of Renal Failure Research, Guangzhou, Guangdong 510515, China.
Jieli YuDivision of Nephrology, Nanfang Hospital, Southern Medical University; State Key Laboratory of Multi-organ Injury Prevention and Treatment; National Clinical Research Center for Kidney Disease; Guangdong Provincial Institute of Nephrology; Guangdong Provincial Key Laboratory of Renal Failure Research, Guangzhou, Guangdong 510515, China.
Pei DengDivision of Nephrology, Nanfang Hospital, Southern Medical University; State Key Laboratory of Multi-organ Injury Prevention and Treatment; National Clinical Research Center for Kidney Disease; Guangdong Provincial Institute of Nephrology; Guangdong Provincial Key Laboratory of Renal Failure Research, Guangzhou, Guangdong 510515, China.
Weiwei XuDivision of Nephrology, Nanfang Hospital, Southern Medical University; State Key Laboratory of Multi-organ Injury Prevention and Treatment; National Clinical Research Center for Kidney Disease; Guangdong Provincial Institute of Nephrology; Guangdong Provincial Key Laboratory of Renal Failure Research, Guangzhou, Guangdong 510515, China.
Bingqian PanDivision of Nephrology, Nanfang Hospital, Southern Medical University; State Key Laboratory of Multi-organ Injury Prevention and Treatment; National Clinical Research Center for Kidney Disease; Guangdong Provincial Institute of Nephrology; Guangdong Provincial Key Laboratory of Renal Failure Research, Guangzhou, Guangdong 510515, China.
Lei ZhangDivision of Nephrology, Nanfang Hospital, Southern Medical University; State Key Laboratory of Multi-organ Injury Prevention and Treatment; National Clinical Research Center for Kidney Disease; Guangdong Provincial Institute of Nephrology; Guangdong Provincial Key Laboratory of Renal Failure Research, Guangzhou, Guangdong 510515, China.
Hong ZhouDivision of Nephrology, Nanfang Hospital, Southern Medical University; State Key Laboratory of Multi-organ Injury Prevention and Treatment; National Clinical Research Center for Kidney Disease; Guangdong Provincial Institute of Nephrology; Guangdong Provincial Key Laboratory of Renal Failure Research, Guangzhou, Guangdong 510515, China.
Jing ZhangDepartment of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China.
Xiaohan LiuDepartment of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China.
Min ShiDepartment of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China.
Xianchi DongSchool of Life Science, Nanjing University, Nanjing, Jiangsu 210023, China.
Bei TongJiangsu Key Laboratory for Conservation and Utilization of Plant Resources, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences (Nanjing Botanical Garden Memorial Sun Yat-Sen), Nanjing 210014, China.
Enguang BiDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Guangdong Provincial Key Laboratory of Single Cell Technology and Application, Southern Medical University, Guangzhou, Guangdong 510515, China.
Nannan GuoKey Laboratory of Mental Health of the Ministry of Education, Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence, Guangdong-Hong Kong Joint Laboratory for Psychiatric Disorders, Guangdong Province Key Laboratory of Psychiatric Disorders, Guangdong Basic Research Center of Excellence for Integrated Traditional and Western Medicine for Qingzhi Diseases, Department of Neurobiology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong 510515, China.
Yu HuDivision of Nephrology, Nanfang Hospital, Southern Medical University; State Key Laboratory of Multi-organ Injury Prevention and Treatment; National Clinical Research Center for Kidney Disease; Guangdong Provincial Institute of Nephrology; Guangdong Provincial Key Laboratory of Renal Failure Research, Guangzhou, Guangdong 510515, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AntibodiesCD4-Positive T-LymphocytesLymphocyte ActivationReceptors, Phospholipase A2AnimalsAntigen PresentationCell LineEndocytosisHumansLysosomesMiceMice, Inbred C57BLAntibodiesPLA2R1 protein, humanReceptors, Phospholipase A2antigen presentationCD4⁺ T cellsclathrin-mediated endocytosisPLA2Rprimary membranous nephropathy

Identifiers

PMID41328348
PMCPMC12665110

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.