Evidence map›Paper›PMID 41328382›Full record

ArticleInternational journal of clinical pediatric dentistry2025

Evaluation of Antimicrobial Efficacy and Cytotoxicity of Phytoextract from

G Pragadesh, Daya Srinivasan, C B Abishek, B K Sujathadevi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of clinical pediatric dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

G PragadeshDepartment of Pediatric and Preventive Dentistry, Chettinad Dental College & Research Institute, Chennai, Tamil Nadu, India.ORCID https://orcid.org/0009-0007-7234-5728
Daya SrinivasanDepartment of Pediatric and Preventive Dentistry, Chettinad Dental College & Research Institute, Chennai, Tamil Nadu, India.ORCID https://orcid.org/0000-0001-5453-4380
C B AbishekDepartment of Pediatric and Preventive Dentistry, Chettinad Dental College & Research Institute, Chennai, Tamil Nadu, India.ORCID https://orcid.org/0009-0004-4014-5906
B K SujathadeviDepartment of Public Health Dentistry, Sathyabama Dental College, Chengalpattu, Tamil Nadu, India.ORCID https://orcid.org/0009-0007-4353-7923

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim and background: Root canal irrigation is a critical step in pediatric endodontics, where an ideal irrigant should exhibit potent antimicrobial properties while maintaining biocompatibility. Sodium hypochlorite (NaOCl) is widely used for its strong antimicrobial efficacy, but its cytotoxic effects raise concerns, especially in pediatric patients. Materials and methods: The antimicrobial efficacy of Results: Antimicrobial efficacy Conclusion: NaOCl's antimicrobial efficacy is concentration-dependent, with higher concentrations providing greater bacterial inhibition but also increasing cytotoxic effects. One percent NaOCl is chosen for pediatric dentistry as it offers a balance between antimicrobial effectiveness and safety. Although Clinical significance: The use of How to cite this article: Pragadesh G, Srinivasan D, Abishek CB,

Indexed as

Antimicrobial efficacyBiocompatibilityCytotoxicityLeucas asperaPediatric dentistryRoot canal irrigationSodium hypochlorite

Identifiers

PMID41328382
PMCPMC12658424

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.