ArticleUltrasonics sonochemistry2026
Combating resilient Acanthamoeba castellanii cysts: Ultrasonic frequency-dependent effects on viability and excystment.
Article in Ultrasonics sonochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Free-living amoebae (FLA) are significant environmental reservoirs for numerous pathogenic microorganisms. These protists exhibit remarkable resilience, often evading biocides due to their ability to form highly resistant dormant cysts under unfavorable conditions. This study investigated the effects of ultrasound treatment on the viability of these amoeba cysts, using Acanthamoeba castellanii, a prevalent water and soil amoeba, as a model. We found that low-frequency ultrasound treatment significantly impaired the revival of Acanthamoeba cysts. In contrast, high-frequency ultrasound effectively ruptured cyst walls and induced direct amoebal death. Further investigation using tert-Butanol, an OH radical scavenger, partially mitigated the effects induced by high-frequency ultrasound, demonstrating that reactive oxygen species contribute to amoeba damages. Our results highlight ultrasound's significant potential as an efficient and effective strategy to combat resilient Acanthamoeba cysts.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.