Evidence map›Paper›PMID 41330642›Full record

ArticleThorax2026

Maternal eating disorders and respiratory outcomes in childhood: findings from the EU Child Cohort Network.

Maja Popovic, Milena Maule, Chiara Moccia, Elena Isaevska, Demetris Avraam, Tim Cadman, Ahmed Elhakeem, Veit Grote, Kathrin Guerlich, Sido Haakma and 11 more

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Article in Thorax, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Maja PopovicCancer Epidemiology Unit, Department of Medical Sciences, University of Turin, Turin, Italy maja.popovic@unito.it.ORCID 0000-0003-4500-6572
Milena MauleCancer Epidemiology Unit, Department of Medical Sciences, University of Turin, Turin, Italy.
Chiara MocciaCancer Epidemiology Unit, Department of Medical Sciences, University of Turin, Turin, Italy.ORCID 0000-0002-7970-8727
Elena IsaevskaCancer Epidemiology Unit, Department of Medical Sciences, University of Turin, Turin, Italy.
Demetris AvraamSection of Epidemiology, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Tim CadmanDepartment of Genetics, Genomics Coordination Center, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Ahmed ElhakeemMRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
Veit GroteDivision of Metabolic and Nutritional Medicine, Department of Paediatrics, Dr. von Hauner Children's Hospital, LMU University Hospital, Ludwig Maximilian University Munich, Munich, Germany.
Kathrin GuerlichDivision of Metabolic and Nutritional Medicine, Department of Paediatrics, Dr. von Hauner Children's Hospital, LMU University Hospital, Ludwig Maximilian University Munich, Munich, Germany.
Sido HaakmaDepartment of Genetics, Genomics Coordination Center, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Jennifer Ruth HarrisCenter for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.
Pauline W JansenDepartment of Child and Adolescent Psychiatry/Psychology, University Medical Centre, Erasmus MC, Rotterdam, The Netherlands.
Johanna Lucia Thorbjørnsrud NaderCenter for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.
Angela Pinot de MoiraSection of Epidemiology, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Katrine Strandberg-LarsenSection of Epidemiology, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Morris SwertzDepartment of Genetics, Genomics Coordination Center, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Marieke WeltenDepartment of Pediatrics, Generation R Study Group, University Medical Center Rotterdam, Erasmus MC, Rotterdam, The Netherlands.
Tiffany YangBradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK.
Vincent JaddoeDepartment of Pediatrics, Generation R Study Group, University Medical Center Rotterdam, Erasmus MC, Rotterdam, The Netherlands.ORCID 0000-0003-2939-0041
Liesbeth DuijtsDepartment of Pediatrics, Division of Respiratory Medicine and Allergology, University Medical Center Rotterdam, Erasmus Medical Center, Rotterdam, The Netherlands.ORCID 0000-0001-6731-9452
Lorenzo RichiardiCancer Epidemiology Unit, Department of Medical Sciences, University of Turin, Turin, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile maternal depression and anxiety have been linked to adverse childhood respiratory outcomes, the role of eating disorders (EDs) remains less understood. This study examined associations between maternal EDs and offspring respiratory outcomes, considering ED subtypes, exposure windows and comorbid depression/anxiety.

methodsData from 131 495 mother-child pairs across seven cohorts from the EU Child Cohort Network were analysed. Primary analyses assessed associations between maternal pre-pregnancy EDs and preschool wheezing and school-age asthma. Secondary analyses explored associations in women without comorbid depression/anxiety, specific ED subtypes (anorexia nervosa, bulimia nervosa), exposure periods (pregnancy, post-pregnancy) and - within two cohorts - school-age lung function. Logistic regression models were fitted for each cohort, and results pooled using random-effects meta-analysis.

resultsMaternal pre-pregnancy ED prevalence ranged from 0.8% (health records) to 17.0% (self-reported lifetime EDs). Preschool wheezing prevalence ranged from 20.7% to 49.6%, and school-age asthma from 2.1% to 17.3%. Pre-pregnancy EDs were associated with preschool wheezing (OR: 1.25, 95% CI: 1.06 to 1.47, I

conclusionsMaternal EDs are associated with a higher risk of wheezing and asthma in children, independently of comorbid depression/anxiety. These findings highlight the need to understand mechanisms and long-term respiratory consequences of maternal EDs to inform interventions for improving offspring respiratory health.

Indexed as

AsthmaFeeding and Eating DisordersMothersPregnancy ComplicationsPrenatal Exposure Delayed EffectsRespiratory SoundsAdultAnxietyChildChild, PreschoolCohort StudiesEuropeFemaleHumansMalePregnancyAsthmaAsthma EpidemiologyChildPaediatric asthma

Identifiers

PMID41330642
PMCPMC13151454

What Socratic holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.