ArticleScientific reports2025
Tissue-specific transcriptomic and endocrine signatures of obligatory reproductive diapause in Eurygaster integriceps.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Molecular characterization and seasonal, sex-associated expression patterns of HSP genes in Eurygaster integriceps (Hemiptera: Scutelleridae).Journal of insect science (Online) · 2026Article
- Characterization and Seasonal Expression Profiling of a Takeout/Juvenile Hormone-Binding Protein-Family Gene Associated With Diapause in Eurygaster integriceps.Archives of insect biochemistry and physiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Obligatory reproductive diapause is a hormonally regulated, developmentally programmed state occurring independently of environmental cues. Despite its prevalence in univoltine insects, the molecular regulation remains unclear. The Sunn pest Eurygaster integriceps (Hemiptera: Scutelleridae), a univoltine wheat and barley pest, alternates between a reproductive phase in early spring and diapause during summer to winter. This study investigated the molecular basis of diapause and reproductive activation in this species. Transcriptomic profiling of brain tissues (including corpora allata and corpora cardiaca) and fat body revealed key components of the juvenile hormone (JH) pathway: juvenile hormone acid methyltransferase (JHAMT), Methoprene-tolerant (Met), and Vitellogenin (Vg). De novo assembly of high-quality RNA-seq data yielded 12,557 and 15,684 contigs from brain and fat body tissues, respectively. BUSCO analysis confirmed completeness of 81.6% and 86.5% of core insect orthologs in these assemblies. The full-length JHAMT cDNA (837 bp) encoded a 278-aa cytoplasmic protein; Met (2031 bp) encoded a 665-aa nuclear protein; and Vg (5220 bp) encoded a 1708-aa secretory protein with a signal peptide. Expression profiling via qPCR revealed synchronized transcriptional dynamics of JHAMT, Met, and Vg, with significantly elevated levels in reproductively active females, and reduced expression during diapause phases. These results indicate that diapause in E. integriceps is orchestrated via a conserved JH-Met pathway, with Vg playing a central role in reproductive competence. This study provides the first molecular evidence for hormonally mediated obligatory diapause in E. integriceps, identifying potential RNAi targets for pest control and offering a model for studying diapause evolution in the Sunn pest.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.