Evidence map›Paper›PMID 41331262›Full record

ReviewNPJ microgravity2025

Stem cells in space: microgravity effects on stem cell fate and implications for regenerative medicine.

Sungmin Kim, KyeongHyeok Min, Yun-Gwi Park, Sung-Hwan Moon

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in NPJ microgravity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sungmin Kim *School of Cellular and Molecular Medicine, University of Bristol, Biomedical Sciences Building, University Walk, Bristol, UK.
KyeongHyeok Min *Department of Animal Biotechnology, College of Biotechnology and Natural Resources, Chung-Ang University, Anseong, Republic of Korea.
Yun-Gwi ParkDepartment of Animal Biotechnology, College of Biotechnology and Natural Resources, Chung-Ang University, Anseong, Republic of Korea.
Sung-Hwan MoonDepartment of Animal Biotechnology, College of Biotechnology and Natural Resources, Chung-Ang University, Anseong, Republic of Korea. moonsh@cau.ac.kr.

Funding

Chung-Ang University Graduate Research Scholarship Academic scholarship for the College of Biotechnology and Natural Resources, 2023Ministry of Science and ICT, the Ministry of Health Welfare, Korean government (Republic of Korea) Korean Fund for Regenerative Medicine (KFRM) grant (25A0203L1)the National Research Foundation of Korea (NRF) the BioMedical Technology Development Program (RS-2023-00220207)
6 · The paper itself

Abstract

Microgravity offers a unique platform for understanding how physical forces influence the fate and function of stem cells. This review integrates recent findings on genomic, epigenetic, and mechanotransductive responses of diverse stem cell types under actual and simulated microgravity conditions. It uniquely relates these biological insights with space-based biomanufacturing, translational applications, and ethical frameworks, highlighting how space-enabled stem cell research advances regenerative medicine both in orbit and on Earth.

Identifiers

PMID41331262
PMCPMC12783672

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.