ArticleTrials2025
Comparing online and face-to-face Liuzijue training in stroke survivors with respiratory dysfunction: study protocol for a randomized controlled non-inferiority trial.
Article in Trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
backgroundStroke is a global health problem, and respiratory dysfunction post-stroke is a common complication that affects the recovery process of patients and their quality of life. In this study, we aim to investigate whether online Liuzijue training is non-inferior to the face-to-face one in terms of training efficacy and patient safety for stroke survivors with respiratory dysfunction. METHODS/
designWe will recruit 64 stroke survivors with respiratory dysfunction from January 2025 and assign them randomly into control, online, and offline groups. In addition to their routine rehabilitation therapy, patients in the online and offline groups will undergo Liuzijue training once a day, 5 days a week, for 8 weeks, while those in the control group will not engage in any Liuzijue training. The primary outcomes will include the forced expiratory volume in one second and peak expiratory flow. Secondary outcomes will include the diaphragmatic thickening fraction during quiet breathing and diaphragmatic excursion during quiet breathing. All outcomes will be measured before and after the intervention. In addition, the incidence of adverse events associated with Liuzijue training will be recorded to assess the safety of the intervention. DISCUSSION: This study provides a simple, feasible, repeatable, and fun exercise training approach. To the best of our knowledge, there are no randomized controlled trials in the existing literature on internet-based respiratory exercise applied to stroke patients. The protocol presented in our study can serve as a reference for an alternative and supplementary approach to long-term inpatient respiratory rehabilitation.
trial registrationChinese Clinical Trial Register, ChiCTR2400094537. Registered on 24 December 2024, https://www.chictr.org.cn/index.html.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.