Evidence map›Paper›PMID 41331806›Full record

ArticleHealth and quality of life outcomes2025

Evaluation of measurement properties of the Health Assessment Questionnaire-Disability Index (HAQ-DI) among gout patients in China.

Nuoming Xu, Tianqi Hong, Chang Luo, Shitong Xie, Jing Wu

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Article in Health and quality of life outcomes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Nuoming XuSchool of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, China.
Tianqi HongSchool of Biomedical Engineering, McMaster University, Hamilton, ON, Canada.
Chang LuoSchool of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, China.
Shitong XieSchool of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, China. xiest@tju.edu.cn.
Jing WuSchool of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, China. jingwu@tju.edu.cn.

Funding

National Natural Science Foundation of China 72404205Natural Science Foundation of Tianjin, China 23JCQNJC01650
6 · The paper itself

Abstract

objectivesTo evaluate measurement properties of Chinese version of the Health Assessment Questionnaire Disability Index (HAQ-DI) among Chinese gout patients.

methodA representative sample of Chinese gout patients were recruited with stratification based on age, sex, urban/rural residence, and education level. Ceiling and floor effects were evaluated. Reliability was assessed by internal consistency (Cronbach’s α). Structural validity was verified by confirmatory factor analysis (CFA). Convergent validity was assessed using Spearman’s rank coefficient, examining the correlation between the HAQ-DI and EQ-5D-5L. Known-groups validity was evaluated by determining the HAQ-DI score differences between subgroup patients. Effect sizes were then used to assess sensitivity of the subgroup differences.

resultsA total of 1,000 patients were included in the study. Ceiling and floor effects were both not observed. Cronbach’s α was 0.95. The factor loadings of CFA were all above 0.6 and the model fit indices were acceptable (χ2/df = 5.97, RMSEA = 0.071, RFI = 0.906, CFI = 0.940, TLI = 0.920), indicating that the eight-factor model had well structural validity. The HAQ-DI correlated in predictable ways with five EQ-5D-5L dimensions, with Spearman’s rank coefficient ranging from 0.30 to 0.61. The HAQ-DI can discriminate between subgroup patients with different levels of health status, with the mean effect size (0.73) at a medium level.

conclusionsChinese version of the HAQ-DI was verified to have satisfactory reliability, validity, and sensitivity in measuring health-related quality of life of Chinese gout patients. We recommend supplementing the responsiveness of the HAQ-DI to changes over time in future research.

Indexed as

Disability EvaluationGoutQuality of LifeAdultAgedChinaFactor Analysis, StatisticalFemaleHealth StatusHumansMaleMiddle AgedPsychometricsReproducibility of ResultsSurveys and QuestionnairesChinaGoutHAQ-DIHealth-related quality of lifeMeasurement propertiesPhysical function

Identifiers

PMID41331806
PMCPMC12781824

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.