ArticleBMC medicine2025
Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) diet and cardiovascular disease and arrhythmias.
Article in BMC medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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Who cites it
1 citing paper in PubMed.
- Beneficial Effects of Olive Oil and the Mediterranean Diet on Alzheimer's Disease and Vascular Dementia: A Review.Medicina (Kaunas, Lithuania) · 2026Review
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to explore associations between the Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) diet and the risk of incident cardiovascular disease (CVD) and arrhythmias, together with comparing to three other pre-existing diet quality indices.
methodsA prospective analysis was conducted using the UK Biobank. MIND diet score, Mediterranean Diet Adherence Screener (MEDAS), Recommended Food Score (RFS), and Healthy Diet Indicator (HDI) were computed using the Oxford WebQ. Cox proportional hazards regression models were used to calculate hazard ratios (HR) and 95% confidence intervals (CI).
results193,983 participants were included in the CVD analyses, and 190,529 for arrhythmias. Compared with participants in the lowest quartile of MIND diet score, participants in the highest quartile had a lower risk of CVD (HR 0.86; 95% CI 0.81-0.91), ischemic heart disease (0.92; 0.85-0.98), stroke (0.86; 0.75-0.97), heart failure (0.79; 0.71-0.88), and total arrhythmias (0.93; 0.88-0.99), after adjusting for demographics, lifestyle, and chronic conditions. With further adjustment for metabolic profiles, the associations remain significant for CVD and its subtypes but become non-significant for arrhythmias. Strengths of association varied across diet scores, with associations for MEDAS (CVD and arrhythmias) and MIND (CVD subtypes). The associations with CVD were linear for MIND and MEDAS and non-linear for RFS. The association between MEDAS and arrhythmias was non-linear. We observed significant interactions by age and obesity for CVD.
conclusionsThe MIND diet was associated with CVD and arrhythmias, relying on a single day of dietary data to derive dietary patterns. The findings suggest that following the MIND diet was associated with a lower risk of CVD, heart failure specifically, and arrhythmias.
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