Evidence mapPaperPMID 41332248Full record

ReviewJournal of leukocyte biology2025

Extracellular vesicles decoying across host immunity.

Jorge J Canas, Samantha M Enslow, Saloni Bhimani, Mariola J Ferraro

Abstract readReview
In one paragraph

Review in Journal of leukocyte biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jorge J CanasDepartment of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, 1355 Museum Rd, Gainesville, FL 32611, United States.
Samantha M EnslowDepartment of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, 1355 Museum Rd, Gainesville, FL 32611, United States.
Saloni BhimaniDepartment of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, 1355 Museum Rd, Gainesville, FL 32611, United States.
Mariola J FerraroDepartment of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, 1355 Museum Rd, Gainesville, FL 32611, United States.ORCID 0000-0003-0459-7716

Funding

The Function of Host-derived Extracellular Vesicles in Trafficking of Bacterial Antigens to Stimulate the Antibacterial Immune ResponseR01AI158749 · UNIVERSITY OF FLORIDA · 2025 to 2025
$474k
NIAID NIH HHS R01 AI158749U.S. National Institute of Allergy and Infectious Diseases R01 AI158749-04
6 · The paper itself

Abstract

Extracellular vesicles (EVs) are essential components for intercellular communication, bioactive cargo trafficking, and homeostasis maintenance. The knowledge regarding the diverse functions and applications of EVs has continually expanded over the recent decade. The classification of eukaryotic EVs based on their biophysical or biochemical properties has failed to adequately capture the variety of biological effects attributed to these micro- and nanovesicles. In this review, we specifically discuss the functional definition of EVs which possess decoying capabilities, including consequential biological interactions with toxins, pathogen- and damage- associated molecular patterns, and nutrients. We focus on the reported studies that highlight recent discoveries involving decoy EVs that intercept host immunity, further focusing on microbial pathogeneses as well as on chronic illnesses. Last, we evaluate biomedical methodologies to suitably address research questions and uncover distinct decoying properties of these decoy EVs across various health and disease experimental settings.

Indexed as

Extracellular VesiclesHost-Pathogen InteractionsImmunityAnimalsCell CommunicationHumanscell communicationdecoy vesiclesextracellular vesicleshost-defenseimmunology

Identifiers

PMID41332248
PMCPMC13105288

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.