ArticlebioRxiv : the preprint server for biology2025
Constraining inference of across-region interactions using neural activity perturbations.
Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Authors and funding
6 authors.
Funding
Abstract
Functional interactions between brain regions are often inferred from multi-region models fit to neural activity recorded in behaving animals. Here, we show that inference of across-region interactions is hindered by the wide breadth of model fits consistent with naturally occurring neural activity. In contrast, models fit to activity that includes region-wide activity perturbations provide well-constrained estimates of across-region interactions; simulations suggest these estimates can be accurate.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.