Evidence map›Paper›PMID 41332710›Full record

ArticlebioRxiv : the preprint server for biology2025

Evaluating the potential of cross-species neutralization of anti-PfCyRPA and anti-PfRIPR Monoclonal Antibodies.

Noemi Guerra, Kelly A Hagadorn, Megha Nair, Laty Gaye Thiam, Barnabas G Williams, Kirsty McHugh, Dimitra Pipini, Julie Healer, Paul Masendycz, Alan F Cowman and 2 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Noemi GuerraYale School of Public Health, Department of Epidemiology of Microbial Diseases, New Haven, CT, 06510, USA.ORCID 0009-0008-8472-7130
Kelly A HagadornYale School of Public Health, Department of Epidemiology of Microbial Diseases, New Haven, CT, 06510, USA.ORCID 0000-0001-7200-7023
Megha NairYale School of Public Health, Department of Epidemiology of Microbial Diseases, New Haven, CT, 06510, USA.ORCID 0009-0008-2499-8860
Laty Gaye ThiamG4-Malaria Experimental Genetic Approaches & Vaccines, Pôle Immunophysiopathologie et Maladies Infectieuses, Institut Pasteur de Dakar, Dakar, Senegal.ORCID 0000-0001-7086-4726
Barnabas G WilliamsDepartment of Paediatrics, University of Oxford, Dorothy Crowfoot Hodgkin Building, Oxford, United Kingdom.ORCID 0000-0002-3078-8076
Kirsty McHughDepartment of Paediatrics, University of Oxford, Dorothy Crowfoot Hodgkin Building, Oxford, United Kingdom.ORCID 0000-0002-5411-7883
Dimitra PipiniKavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, United Kingdom.ORCID 0000-0002-2230-6364
Julie HealerThe Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.ORCID 0000-0001-8917-6237
Paul MasendyczThe Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
Alan F CowmanThe Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.ORCID 0000-0001-5145-9004
Simon J DraperDepartment of Paediatrics, University of Oxford, Dorothy Crowfoot Hodgkin Building, Oxford, United Kingdom.ORCID 0000-0002-9415-1357
Amy K BeiYale School of Public Health, Department of Epidemiology of Microbial Diseases, New Haven, CT, 06510, USA.ORCID 0000-0003-1159-760X

Funding

NRSA Training CoreTL1TR001864 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$9.9M
Evaluating the Functional Impact of Genetic Diversity on Malaria Vaccine CandidatesR01AI168238 · NIAID · YALE UNIVERSITY · PI Amy Kristine Bei · 2022 to 2026
$3.5M
The Kinetics and Dynamics of Functional Immune Responses to Plasmodium falciparum StrainsF31AI176818 · NIAID · YALE UNIVERSITY · PI Kelly Hagadorn · 2024 to 2026
$119k
NCATS NIH HHS TL1 TR001864NIAID NIH HHS F31 AI176818NIAID NIH HHS R01 AI168238
6 · The paper itself

Abstract

PfCyRPA and PfRIPR are promising next-generation malaria blood-stage vaccine candidate antigens that play an essential role in erythrocyte invasion of

Identifiers

PMID41332710
PMCPMC12668661

What Socratic holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.