Evidence map›Paper›PMID 41332789›Full record

ArticlebioRxiv : the preprint server for biology2025

Tom70-mediated mitochondria-nuclear envelope contacts regulate nuclear pore complex inheritance during gametogenesis.

Cyrus T Ruediger, Benjamin S Styler, Eric M Sawyer, Silvan Spiri, Grant King, Madison E Walsh, Gloria A Brar, Danielle M Jorgens, Elçin Ünal

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cyrus T RuedigerDepartment of Molecular and Cell Biology, University of California, Berkeley, CA, 94720, USA.ORCID 0000-0001-6054-3806
Benjamin S StylerDepartment of Molecular and Cell Biology, University of California, Berkeley, CA, 94720, USA.ORCID 0000-0002-0458-8230
Eric M SawyerDepartment of Molecular and Cell Biology, University of California, Berkeley, CA, 94720, USA.ORCID 0000-0003-1160-3838
Silvan SpiriDepartment of Molecular and Cell Biology, University of California, Berkeley, CA, 94720, USA.ORCID 0000-0002-7124-3056
Grant KingDepartment of Molecular and Cell Biology, University of California, Berkeley, CA, 94720, USA.ORCID 0000-0001-9854-3174
Madison E WalshDepartment of Molecular and Cell Biology, University of California, Berkeley, CA, 94720, USA.
Gloria A BrarDepartment of Molecular and Cell Biology, University of California, Berkeley, CA, 94720, USA.ORCID 0000-0002-8560-9581
Danielle M JorgensElectron Microscope Lab, University of California, Berkeley.ORCID 0000-0002-7143-0118
Elçin ÜnalDepartment of Molecular and Cell Biology, University of California, Berkeley, CA, 94720, USA.ORCID 0000-0002-6768-609X

Funding

THE MOLECULAR BASIS OF CELL FUNCTIONT32GM007232 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BILDER, DAVID, UNAL, ELCIN · 1985 to 2022
$36.4M
POSTGRADUATE TRAINING PROGRAM IN GENETICST32GM007127 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI DILLIN, ANDREW G · 1985 to 2016
$7.9M
Genetic Dissection of Cells and Organisms Training ProgramT32GM132022 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Nicole King, NOAH K WHITEMAN · 2019 to 2026
$5.2M
Illuminating the gene regulatory strategies underlying yeast meiosis and beyondR35GM134886 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Gloria Ann Brar · 2020 to 2026
$3.1M
Defining the programmed proteome rejuvenation underlying gametogenesisR01AG071869 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI BRAR, GLORIA ANN, JOVANOVIC, MARKO · 2021 to 2025
$2.9M
Elucidating Cellular Aging and Quality Control Pathways through Meiotic DifferentiationR01AG071801 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI UNAL, ELCIN · 2021 to 2025
$1.9M
NIA NIH HHS R01 AG071801NIA NIH HHS R01 AG071869NIGMS NIH HHS R35 GM134886NIGMS NIH HHS T32 GM007127NIGMS NIH HHS T32 GM007232NIGMS NIH HHS T32 GM132022
6 · The paper itself

Abstract

Gametogenesis rejuvenates the cellular lineage and excludes senescence-associated factors from gametes. In

Indexed as

Cnm1gametogenesismeiosismembrane contactmitochondrianuclear pore complexorganelle tetherquality controlTom70

Identifiers

PMID41332789
PMCPMC12667904

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.