Evidence map›Paper›PMID 41333288›Full record

ArticlePeerJ2025

Prevalence and association testing of antinuclear antibodies and inflammatory bowel disease in Taiwan.

Tsai-Min Yang, Fang-Ting Lu, Hsu-Heng Yen, Yang-Yuan Chen

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In one paragraph

Article in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tsai-Min Yang *Division of Gastroenterology, Changhua Christian Hospital, Changhua, Taiwan.
Fang-Ting Lu *Frontier Molecular Medical Research Center in Children, Changhua Christian Children Hospital, Changhua, Taiwan.
Hsu-Heng YenDivision of Gastroenterology, Changhua Christian Hospital, Changhua, Taiwan.ORCID 0000-0002-3494-2245
Yang-Yuan ChenDivision of Gastroenterology, Changhua Christian Hospital, Changhua, Taiwan.ORCID 0000-0001-5936-7112

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are characterized by chronic inflammation of the gastrointestinal tract. Antinuclear antibodies (ANAs), which are autoantibodies directed against nuclear components, are commonly present in various autoimmune disorders. We investigated the prevalence and clinical significance of ANAs in Taiwanese patients with IBD. Methods: From January 2017 to December 2024, ANA status was checked at initial diagnosis of IBD in patients from a medical center in central Taiwan. Risk factors for ANA positivity were evaluated. Results: Of the 166 patients in this study, 57 had CD and 109 had UC. ANA test results were positive (titers of ≥ 1:160) in 26 patients (15.7%). Older age at disease diagnosis ( Conclusions: These findings suggest that although ANA positivity is relatively common among Taiwanese patients with IBD, particularly among older UC patients. Further validation is required to explore the clinical implications of ANA positivity in Asian population.

Indexed as

Antibodies, AntinuclearColitis, UlcerativeCrohn DiseaseInflammatory Bowel DiseasesAdultAgedFemaleHumansMaleMiddle AgedPrevalenceRisk FactorsTaiwanYoung AdultAntibodies, AntinuclearAnti-nuclear antibodyAutoimmuneCrohn’s diseaseInflammatory bowel diseaseUlcerative colitis

Identifiers

PMID41333288
PMCPMC12667684

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.