Evidence map›Paper›PMID 41333744›Full record

ArticleVeterinary world2025

Development and evaluation of a formaldehyde-stabilized tuberculin as a safe and potent alternative to phenol-based purified protein derivative for the diagnosis of animal tuberculosis.

Kairat Turgenbayev, Assiya Borsynbayeva, Amanbek Ozatbekuly, Sairan Dyusenov, Anarbek Tlepov, Rauan Turgenbayev

Abstract read
In one paragraph

Article in Veterinary world, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Epidemiological investigation ofOpen veterinary journal · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kairat TurgenbayevBioVet Scientific and Production Center, Almaty, Kazakhstan.
Assiya BorsynbayevaBioVet Scientific and Production Center, Almaty, Kazakhstan.
Amanbek OzatbekulyBioVet Scientific and Production Center, Almaty, Kazakhstan.
Sairan DyusenovBioVet Scientific and Production Center, Almaty, Kazakhstan.
Anarbek TlepovBioVet Scientific and Production Center, Almaty, Kazakhstan.
Rauan TurgenbayevBioVet Scientific and Production Center, Almaty, Kazakhstan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: Bovine tuberculosis (bTB), caused by Materials and Methods: Tuberculin was prepared from Results: Formaldehyde at 3% yielded the highest biological activity and stability without local irritation. In Conclusion: Replacing phenol with 3% formaldehyde significantly enhanced the sensitivity, stability, and biosafety of tuberculin without compromising specificity. The new formulation eliminates phenol toxicity while improving diagnostic yield in animal TB screening. These findings support the integration of formaldehyde-stabilized tuberculin into national and international diagnostic standards as a reliable and safer alternative for large-scale veterinary applications.

Indexed as

biosafetybovine tuberculosisdiagnostic sensitivityformaldehyde stabilizationMycobacterium bovispurified protein derivativetuberculinveterinary diagnostics

Identifiers

PMID41333744
PMCPMC12668726

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.