ReviewJournal of current ophthalmology
Ocular Biometric Findings in Thalassemia Major: A Systematic Review and Meta-Analysis.
Review in Journal of current ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To find the effect of thalassemia major on ocular biometric parameters including axial length (AL), anterior chamber depth (ACD), vitreous chamber depth (VCD), and lens thickness (LT). Methods: A systematic search was carried out on PubMed, Cochrane, and Embase using a combination of keywords. The identified records undergone primary and secondary screening. The meta-analysis was done for comparing AL, ACD, VCD, and LT between thalassemia major cases and controls using pooled effect size, confidence intervals (CIs), quality assessment, and publication bias. This review was registered in the international prospective register of systematic reviews bearing code CRD42024542894. Results: This meta-analysis included 7 studies with a total sample of 1676 individuals (cases = 851, controls = 825). The cases were having reduced AL, ACD, and VCD while increased LT compared to controls. The estimated average effect size for AL = 1.07 (95%CI: 0.47-1.68, z = 3.471, Conclusion: This study concludes that AL, ACD, and VCD were significantly less while LT was significantly greater in cases than in controls.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.