ArticleDrug design, development and therapy2025
The Predictive Value of Initial Trough Concentration of Voriconazole and Procalcitonin in Hepatotoxic Adverse Events.
Article in Drug design, development and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Voriconazole therapeutic drug monitoring and safety in HIV-infected patients with invasive fungal disease.Frontiers in pharmacology · 2026Article
- Voriconazole pseudotoxicity: a case report highlighting the importance of sampling timing in TDM interpretation by clinical pharmacists.Frontiers in medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: This study aimed to evaluate the predictive value of initial trough concentration (C Patients and Methods: A retrospective analysis was performed on clinical data from 170 patients administered VCZ at our institution between January 2021 and July 2025. Risk factors associated with VCZ-induced hepatotoxicity were identified through binary logistic regression analysis. The diagnostic performance of initial VCZ-C Results: The mean loading dose of VCZ was 9.48 mg/kg, with a maintenance dose of 6.62 mg/kg, and an average initial C Conclusion: VCZ-induced hepatotoxicity is the common adverse reaction, exhibiting significant associations with elevated initial VCZ-C
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Registered trials
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