Evidence map›Paper›PMID 41334530›Full record

ReviewIBRO neuroscience reports2025

Neural changes in microgravity: Investigating the effects of aerospace environments.

Fateme Arjmand, Soroush Taherkhani, Aidin Shahrezaei, Maryam Sohani, Sanaz Sadeghi Esfahani, Sepideh Marjaei, Farinaz Nasirinezhad

Abstract readReview
In one paragraph

Review in IBRO neuroscience reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fateme ArjmandReproductive Sciences and Technology Research Center, Department of Anatomical Sciences, Iran University of Medical Sciences, Tehran, Iran.
Soroush TaherkhaniDepartment of Physiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Aidin ShahrezaeiSchool of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Maryam SohaniSchool of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Sanaz Sadeghi EsfahaniDepartment of Molecular Biotechnology, Cell Science Research Center, Royan Institute for Biotechnology, ACECR, Isfahan, Iran.
Sepideh MarjaeiDepartment of Electrical, Computer, Information Technology and Biomedical Engineering, Qazvin Islamic Azad University, Qazvin, Iran.
Farinaz NasirinezhadCenter of Experimental and Comparative Study, Iran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Technological, human, and financial advances have led to an increase in space exploration and, as a result, commercial space travel. Companies such as Space X and Blue Origin are exploring ways to make space travel possible. As a result, the number of patients with space-related neurological disorders may increase. Therefore, the management of neurological disorders in high-risk patients requires a thorough understanding of spaceflight exposure. The neural system physiology is significantly impacted by aerospace environments through various mechanisms including hypoxia, decompression sickness, cardiovascular system adaptations to microgravity and acceleration forces. These effects underscore the importance of understanding and mitigating these physiological changes to ensure the safety and well-being of individuals operating in aerospace environments. Potential benefits of spaceflight on the nervous system include psychological growth and improvements in memory and learning. Future space travelers who lack the physiological reserve of current astronauts may experience neurological problems as a result of the physiological and psychological stresses of space travel. As we continue to understand more about human adaptation to microgravity and the potential medical problems that may arise, the capabilities of healthcare must continue to progress to match the ambition of multinational corporations. In conclusion, there appear to be many factors that can affect the nervous system and lead to neurological diseases in people who travel to space. As space travel becomes more accessible to the general public these nervous system effects will need to become a staple of the future neurologist's clinical practice.

Indexed as

Aerospace environmentsBrain activityMicrogravityNeural system

Identifiers

PMID41334530
PMCPMC12666590

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.