ArticleGlobal spine journal2026
External Validation of the SITE Score for De Novo Spinal Infections: A Retrospective Cohort Study.
Article in Global spine journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Clinical characteristics, microbiological landscape, and severity-stratified management of pyogenic spondylitis: a retrospective cohort study.Frontiers in cellular and infection microbiology · 2026Observational
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Study DesignRetrospective Cohort Study.ObjectiveDe novo spinal infections (DNSI) require prompt treatment decisions, especially on conservative or surgical management. The Spinal Infection Treatment Evaluation (SITE) score was developed in 2022 to standardize treatment recommendations, but external validation remains limited.MethodsIn a retrospective, single-center study, we analyzed consecutive patients with DNSI treated between January 2016 and December 2022. We calculated SITE scores based on admission parameters and compared score-based treatment recommendations with actual clinical decisions. The primary outcome was concordance between SITE recommendations and treatment decisions. Secondary outcomes included individual component performance and discriminatory ability, as assessed using receiver operating characteristic analysis.ResultsWe identified 95 patients with DNSI (mean age 66.4, 66.3% male). SITE scores ranged from 4-13 points. Treatment concordance with SITE recommendations was noticed in 82.1% of cases. In multivariate analysis, neurological status (OR 0.48,
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