Evidence mapPaperPMID 41338990Full record

ArticleExperimental animals2026

Neu5Ac promotes high-fat diet-induced progression of atherosclerosis in ApoE-deficient mice.

Dong Huang, Chengyong Yin, Di Wang

Abstract read
In one paragraph

Article in Experimental animals, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dong HuangDepartment of Cardiovascular Surgery, the Second Affiliated Hospital of Kunming Medical University, 374 Dianmian Avenue, Wuhua District, Kunming, Yunnan Province, 650101, P.R. China.
Chengyong YinDepartment of Cardiovascular Surgery, the Second Affiliated Hospital of Kunming Medical University, 374 Dianmian Avenue, Wuhua District, Kunming, Yunnan Province, 650101, P.R. China.
Di WangDepartment of Cardiovascular Surgery, the Second Affiliated Hospital of Kunming Medical University, 374 Dianmian Avenue, Wuhua District, Kunming, Yunnan Province, 650101, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis (AS) is a chronic inflammatory disorder underlying most cardiovascular events sialic acid (SIA), a terminal metabolite of glycolipid catabolism, modulates vascular injury, but its role in endothelial dysfunction remains unclear. To investigate whether N-acetylneuraminic acid (Neu5Ac) accelerates AS development. ApoE

Indexed as

Apolipoproteins EAtherosclerosisDiet, High-FatN-Acetylneuraminic AcidAnimalsDisease ProgressionInflammationMacrophagesMaleMiceMice, Inbred C57BLMice, KnockoutPlaque, AtheroscleroticApolipoproteins EN-Acetylneuraminic Acidatherosclerosisinflammationlipid metabolismmacrophage polarizationN-acetylneuraminic acid (Neu5Ac)

Identifiers

PMID41338990
PMCPMC13100702

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.