Evidence map›Paper›PMID 41339432›Full record

ArticleScientific reports2025

The association between vegetable-derived nitrate and nitrite intake, cardiovascular risk factors and glycemic markers in obese individuals.

Amr Ali Mohamed Abdelgawwad El-Sehrawy, Ahmed Hjazi, Ahad Nourmohammad, Enwa Felix Oghenemaro, Subasini Uthirapathy, Jadhav Balaji, Himani Punia, M Ravi Kumar, Ashish Singh Chauhan, Faria Jafarzadeh

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Amr Ali Mohamed Abdelgawwad El-SehrawyDepartment of Internal Medicine, Diabetes, Endocrinology and Metabolism, Mansoura University, Mansoura, Egypt.
Ahmed HjaziDepartment of Medical Laboratory, College of Applied Medical Sciences, Princse Sattam Bin Abdulaziz University, Al-Kharj, 11942, Saudi Arabia. hjaziahmed36@gmail.com.
Ahad NourmohammadCardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Enwa Felix OghenemaroDepartment of Pharmaceutical Microbiology, Faculty of Pharmacy, Delta State University, PMB 1, Abraka, Delta State, Nigeria.
Subasini UthirapathyPharmacy Department, Tishk International University, Erbil, Kurdistan Region, Iraq.
Jadhav BalajiNIMS School of Food and Agricultural Engineering, NIMS University Rajasthan, Jaipur, India.
Himani PuniaDepartment of Biotechnology, Chandigarh Engineering College, Chandigarh Group of Colleges-Jhanjeri, Mohali, 140307, Punjab, India.
M Ravi KumarDepartment of Basic Science & Humanities, Raghu Engineering College, Visakhapatnam, India.
Ashish Singh ChauhanDivision of Research and Innovation, Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun, Uttarakhand, India.
Faria JafarzadehDepartment of Internal Medicine, North Khorasan University of Medical Sciences, Bojnourd, Iran. fJafarzadeh@nkums.ac.ir.

Funding

Tishk International University RC/ TIU/ SU/ 2025/4052025
6 · The paper itself

Abstract

Although plant-derived nitrates and nitrites are increasingly recognized for their potential metabolic advantages, current research presents mixed outcomes. This study explores the relationship between vegetable-sourced nitrate and nitrite consumption and key metabolic indicators in overweight and obese Iraqi adults. A total of 338 individuals participated in a cross-sectional analysis, completing a validated food frequency questionnaire to quantify their intake of nitrates and nitrites from vegetables. Blood pressure readings were obtained using standard sphygmomanometer, and biochemical markers-including fasting glucose, lipid profile, and insulin-were assessed via enzymatic assays. Participants with the highest intake of vegetable nitrates demonstrated significantly lower systolic blood pressure compared to those with the lowest intake (P < 0.05). Likewise, elevated dietary nitrite consumption was linked to lower fasting glucose and total cholesterol levels, alongside increased HDL cholesterol (P < 0.05), across both crude and adjusted statistical models. Elevated intake of nitrates and nitrites from vegetables appears to be associated with favorable cardiovascular and metabolic health markers in overweight and obese individuals. These results highlight the potential of vegetable-based nitrate and nitrite consumption as a dietary strategy for improving cardio-metabolic outcomes, meriting further investigation through longitudinal studies.

Indexed as

Blood GlucoseCardiovascular DiseasesNitratesNitritesObesityVegetablesAdultBiomarkersBlood PressureCross-Sectional StudiesDietFemaleHeart Disease Risk FactorsHumansMaleMiddle AgedBiomarkersBlood GlucoseNitratesNitritesBlood pressureDietGlycemic statusHypertensionNitrate

Identifiers

PMID41339432
PMCPMC12780158

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.