ArticleNature2026
Architecture of the neutrophil compartment.
Abstract read
In one paragraph
Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Dynamic single-cell landscape reveals a T-cell-suppressed microenvironment and a conserved neutrophil program in the lung metastatic niche.Genes & diseases · 2026Article
- The role of IRF5 as an immune regulator.Biochemical Society transactions · 2026Review
- Single-cell and spatial transcriptomics identify a JUNB+ neutrophil subset enriched in immune-excluded regions of lung adenocarcinoma.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026Article
- Granulocyte heterogeneity in immune-mediated and inflammatory diseases: insights from single-cell transcriptomic analyses.International immunology · 2026Review
- Neutrophil-driven immunosuppression in cancer.Cell insight · 2026Review
- Leveraging Microphysiological Systems to Facilitate Neutrophil-Based Cancer Immunotherapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Neutrophils in cancer.Nature reviews. Cancer · 2026Review
- Emergency granulopoiesis and innate immune memory in inflammatory bowel disease.Trends in immunology · 2026Review
- Advances in Chinese herbal medicine for diabetic wound treatment: from tradition to innovation.Chinese medicine · 2026Review
- Airway immune signatures of protection and disease progression in recent human tuberculosis household contacts.Nature immunology · 2026Article
- Depth of neutrophil mobilization stratifies survival in ST-elevation myocardial infarction.Nature cardiovascular research · 2026Article
- From Bone Marrow Reserve to Metastatic Niche: How Neutrophil-Lineage Cells Shape Skeletal Colonization.International journal of molecular sciences · 2026Review
- Striping artifact removal in VisiumHD data through nuclear counts modeling.Bioinformatics (Oxford, England) · 2026Article
- Engineered Neutrophils in Translational Medicine: Gene Editing, Nanotechnology, and AI-Driven Clinical Breakthroughs.Advanced healthcare materials · 2026Review
- Threat assessment shapes neutrophil cell fate upon inflammasome activation.Science advances · 2026Article
- Roles of neutrophil extracellular traps in cancer immunotherapy resistance and therapeutic targeting.Biomarker research · 2026Review
- Immune development in early life.Nature immunology · 2026Review
- Review
- Quantifying the Dual Effect of Antitumor and Pro-Tumor Human Neutrophils on Natural Killer Cell Behaviors in a Microphysiological System.ACS biomaterials science & engineering · 2026Article
- Galectin-9Aging cell · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
63 authors.
Daniela Cerezo-Wallis *Vascular Biology and Therapeutics Program and Department of Immunobiology, Yale University, New Haven, CT, USA.ORCID 0000-0002-4265-6898
Andrea Rubio-Ponce *Vascular Biology and Therapeutics Program and Department of Immunobiology, Yale University, New Haven, CT, USA.ORCID 0000-0002-4275-8835
Mathis RichterInstitute for Experimental Pathology (ExPat), Centre for Molecular Biology of Inflammation (ZMBE), University of Münster, Münster, Germany.ORCID 0000-0002-3110-6137
Emanuele PitinoCentre Nacional d'Anàlisi Genòmica, Barcelona, Spain.ORCID 0000-0002-1726-5924
Immanuel KwokSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8 A Biomedical Grove, Immunos, Singapore, Singapore.
Giovanni MartelettoVascular Biology and Therapeutics Program and Department of Immunobiology, Yale University, New Haven, CT, USA.ORCID 0009-0000-3526-1153
Ana Cristina Guanolema-CobaCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.ORCID 0009-0008-9312-8535
Changming ShihShanghai Immune Therapy Institute, Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital, Shanghai, China.
Run-Kai HuangShanghai Immune Therapy Institute, Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital, Shanghai, China.
Ana MoragaCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.
Natalia Borbaran BravoDepartment of Oncology, Haematology, Clinical Immunology and Rheumatology, University Hospital, Tübingen, Germany.
Samuel DoréRosalind and Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, Canada.
Sergio CallejasCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.ORCID 0000-0003-3351-4940
David G AragonésDepartment of Mathematics and MOLAB-Mathematical Oncology Laboratory, Universidad de Castilla-La Mancha, Ciudad Real, Spain.ORCID 0000-0003-4035-0972
Daniel Jiménez-CarreteroCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.
Daniel MartinCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.ORCID 0000-0001-6125-2955
Samuel OvadiaVascular Biology and Therapeutics Program and Department of Immunobiology, Yale University, New Haven, CT, USA.ORCID 0000-0002-6604-006X
Tommaso VicanoloCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.
Georgiana CrainiciucCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.
Jon SiciliaCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.
Tong DengVascular Biology and Therapeutics Program and Department of Immunobiology, Yale University, New Haven, CT, USA.
Anjelica MartinVascular Biology and Therapeutics Program and Department of Immunobiology, Yale University, New Haven, CT, USA.ORCID 0000-0001-9669-8842
Jing ZhangDepartment of Health Sciences and Technology, Laboratory of Exercise and Health, ETH Zürich, Zurich, Switzerland.
Maria Isabel CuarteroCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.
Diego Moncada GiraldoDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.
Alicia Garcia-CulebrasCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.
Alejandra Aroca-CrevillenCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.ORCID 0000-0002-2481-0863
Sandra Martín-SalamancaCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.
Carlos TorrojaCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.ORCID 0000-0001-8914-3400
Max RuizCentre Nacional d'Anàlisi Genòmica, Barcelona, Spain.
Irene RuanoCentre Nacional d'Anàlisi Genòmica, Barcelona, Spain.ORCID 0000-0001-9428-2368
Melissa S F NgSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8 A Biomedical Grove, Immunos, Singapore, Singapore.ORCID 0000-0003-3826-2746
Jian HouDepartment of Hematology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
You WangDepartment of Obstetrics and Gynecology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Ming ZhangDepartment of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Jun PuState Key Laboratory for Systems Medicine for Cancer, Division of Cardiology, Shanghai Cancer Institute, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Ana HerruzoMedia and Immersive Experience Center, The Design School, Arizona State University, Arizona State University, Temple, AZ, USA.
David Chang van OordtEcology and Evolutionary Biology, Princeton University, Princeton, NJ, USA.ORCID 0000-0001-6505-2299
Seokyoon ChangEcology and Evolutionary Biology, Princeton University, Princeton, NJ, USA.
Alexander E DownieEcology and Evolutionary Biology, Princeton University, Princeton, NJ, USA.ORCID 0000-0002-6743-620X
Fei ChenDepartment of Medicine, Center for Immunity and Inflammation, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, USA.
Andrea L GrahamEcology and Evolutionary Biology, Princeton University, Princeton, NJ, USA.ORCID 0000-0002-6580-2755
William C GauseDepartment of Medicine, Center for Immunity and Inflammation, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, USA.ORCID 0000-0002-8062-4790
Pierre O FisetDepartment of Pathology, McGill University, Montreal, Quebec, Canada.
Jonathan D SpicerDepartment of Surgery, McGill University Health Center, Montreal, Quebec, Canada.ORCID 0000-0003-2708-1309
Holger HeynCentre Nacional d'Anàlisi Genòmica, Barcelona, Spain.ORCID 0000-0002-3276-1889
Maria A ZuriagaCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.
Juan A BernalCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.ORCID 0000-0002-9933-5550
Irina A UdalovaKennedy Institute of Rheumatology, University of Oxford, Oxford, UK.ORCID 0000-0002-6716-2528
Maria A MoroCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.ORCID 0000-0003-1010-8237
Katrien de BockDepartment of Health Sciences and Technology, Laboratory of Exercise and Health, ETH Zürich, Zurich, Switzerland.ORCID 0000-0001-8232-4663
Ana DopazoCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.ORCID 0000-0002-4910-1684
Jose J FusterCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.ORCID 0000-0002-5970-629X
Fátima Sánchez-CaboCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.ORCID 0000-0003-1881-1664
Juan C NietoCentre Nacional d'Anàlisi Genòmica, Barcelona, Spain.ORCID 0000-0002-3400-1488
Gabriel F CalvoDepartment of Mathematics and MOLAB-Mathematical Oncology Laboratory, Universidad de Castilla-La Mancha, Ciudad Real, Spain.ORCID 0000-0002-3623-236X
Julia SkokowaDepartment of Oncology, Haematology, Clinical Immunology and Rheumatology, University Hospital, Tübingen, Germany.ORCID 0000-0002-4399-2324
Oliver SoehnleinInstitute for Experimental Pathology (ExPat), Centre for Molecular Biology of Inflammation (ZMBE), University of Münster, Münster, Germany.ORCID 0000-0002-7854-0694
Daniela F QuailRosalind and Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, Canada.ORCID 0000-0002-6969-3250
Logan A WalshRosalind and Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, Canada.ORCID 0000-0001-8771-2577
Lai Guan NgShanghai Immune Therapy Institute, Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital, Shanghai, China. nglaiguan@renji.com.ORCID 0000-0003-1905-3586
Andrés HidalgoVascular Biology and Therapeutics Program and Department of Immunobiology, Yale University, New Haven, CT, USA. andres.hidalgo@yale.edu.ORCID 0000-0001-5513-555X
Iván BallesterosCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain. ivballes@salud.uc3m.es.ORCID 0000-0002-6246-2353
Funding
Severe Chronic Neutropenia International RegistryR24AI049393 · NIAID · UNIVERSITY OF WASHINGTON · PI DALE, DAVID CHANDLER · 2004 to 2019
$10.6MSevere Chronic Neutropenia International RegistryR24AI162637 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI PETER E NEWBURGER, Akiko Shimamura · 2022 to 2026
$5.8MNon-canonical functions of neutrophilsR01AI165661 · NIAID · YALE UNIVERSITY · PI HIDALGO, ANDRES · 2022 to 2025
$2.8MNIAID NIH HHS R01 AI165661NIAID NIH HHS R24 AI049393NIAID NIH HHS R24 AI162637
Abstract
Neutrophils exhibit remarkable phenotypic and functional diversity across tissues and diseases
Indexed as
NeutrophilsAnimalsChromatinFemaleGene Expression ProfilingHumansInflammationMaleMiceMice, Inbred C57BLNeoplasmsSingle-Cell AnalysisTransforming Growth Factor betaChromatinTransforming Growth Factor beta
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.