Evidence map›Paper›PMID 41340076›Full record

ReviewJournal of translational medicine2025

Emerging versatile nanozymes for the therapeutic and diagnostic applications of diseases.

Xinhao Jin, Fangxiao Guo, Mingyang Wu, Chengxi Xu, Yiming Li, Guanhui Chen

Abstract readReview
In one paragraph

Review in Journal of translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xinhao Jin *Department of Stomatology, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, PR China.
Fangxiao Guo *Department of Stomatology, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, PR China.
Mingyang WuDepartment of Stomatology, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, PR China.
Chengxi XuDepartment of Stomatology, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, PR China.
Yiming LiDepartment of Stomatology, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, PR China. liym228@mail.sysu.edu.cn.ORCID 0000-0001-6361-6900
Guanhui ChenDepartment of Stomatology, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, PR China. chengh86@mail.sysu.edu.cn.

Funding

National Natural Science Foundation of China 82303794Shenzhen Science and Technology Innovation Program JCYJ20240813150220026
6 · The paper itself

Abstract

Nanozyme has become a new rising star in the medical field because of its high stability, strong catalysis, ease of modification and manufacturing compared with natural enzyme. Nanozyme can regulate reactive oxygen species (ROS), such as down-regulation in inflammation and up-regulation in tumor. Nanozyme plays an important role in treatment of various diseases due to this ability. Additionally, nanozyme can corporate with traditional and novel therapies, which are of tremendous help in both therapeutic and diagnostic aspects. In this review, we summarize the classification and mechanism of action of nanozyme, and its therapeutic and diagnostic applications in various diseases, especially focusing on its potential application for inflammation related diseases, cancer, neurological disorders, cardiovascular diseseases, metabolic diseases, infectious diseases, artificial implants and biomedical detection.

Indexed as

EnzymesNanostructuresAnimalsCardiovascular DiseasesCommunicable DiseasesHumansInflammationMetabolic DiseasesNeoplasmsNervous System DiseasesReactive Oxygen SpeciesEnzymesReactive Oxygen SpeciesInflammationNanomaterialsNanozymesReactive oxygen species

Identifiers

PMID41340076
PMCPMC12676819

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.