Evidence map›Paper›PMID 41340658›Full record

ArticleFrontiers in nutrition2025

Extracellular mass to body cell mass ratio association to nutritional and functional status in middle-aged and older adults.

Antonella Cano, Lucia Ventura, Maria Grazia Catte, Elena Castiglia, Josetta Sanna, Gianluca Martinez, Carmen Oneto, Nicola Loi, Francesca Ginatempo, Andrea Manca and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Antonella CanoAzienda Ospedaliero Universitaria di Sassari, AOUSS, Sassari, Italy.
Lucia VenturaAzienda Ospedaliero Universitaria di Sassari, AOUSS, Sassari, Italy.
Maria Grazia CatteDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.
Elena CastigliaDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.
Josetta SannaDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.
Gianluca MartinezDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.
Carmen OnetoDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.
Nicola LoiAzienda Ospedaliero Universitaria di Sassari, AOUSS, Sassari, Italy.
Francesca GinatempoDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.
Andrea MancaDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.
Franca DeriuDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Poor nutrition and progressive loss of muscle mass is frequent in older individuals. Extracellular mass to body cell mass ratio (ECM/BCM), an easy to calculate index obtained by bioelectrical impedance vector analysis (BIVA), is a parameter of catabolism or extracellular mass expansion, mainly studied in pathological conditions. The aim of the study was to characterize ECM/BCM ratio and its association to indexes of nutritional and functional status in middle-aged and community dwelling older individuals. Methods: Participants aged 51-89 years old ( Results: ECM/BCM mean value was 0.91 ± 0.12. Higher values were observed in women and in individuals over 75. Subjects displaying ECM/BCM above median, presented significantly lower MNA score, PNI, GNRI, and MQI (all Discussion: Herein, ECM/BCM has been associated, after adjusting for cofounding factors as age and sex, to subjective and objective indexes of health, nutritional and functional status in middle-aged and community dwelling older adults. With an integrated perspective, it could represent an easy to calculate, objective index to assess and monitor health, nutritional and functional status in this population.

Indexed as

agingbody compositionextracellular mass to body cell mass ratiogeriatric nutritional risk indexmini nutritional assessmentmuscle quality indexprognostic nutritional index

Identifiers

PMID41340658
PMCPMC12668956

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.