ArticleFrontiers in oncology2025
Automated ITSS extraction combined with R2* values obtained from enhanced T2*-weighted angiography in magnetic resonance imaging: a promising approach for differentiate cervical adenocarcinoma from squamous carcinoma.
Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: This study aims to evaluate the efficacy of utilizing automated intertumoral susceptibility signal (ITSS) intensity extraction combined with R2* values derived from enhanced T2*-weighted angiography (ESWAN) in magnetic resonance imaging (MRI) to distinguish between cervical adenocarcinoma (CA) and cervical squamous carcinoma (CSC). Methods: Seventy-eight patients who underwent ESWAN from 2014 to 2019 were stratified into two groups: CA (26 patients) and CSC (52 patients). R2* values of the lesions were measured, and ITSS ratios were automatically calculated using the Anatomy Sketch (AS) software. Independent samples t-tests or Mann-Whitney U-tests were utilized to evaluate disparities in the parameters. Binary logistic regression was conducted to identify independent predictors. The receiver operating characteristic curve was employed to assess diagnostic value, and the Delong test was applied to compare differences in the area under the curve (AUC). Results: The CA group exhibited significantly higher values for the ITSSs, ITSSv and R2* value, lower alpha fetoprotein (AFP) and prognostic nutritional index (PNI) (ITSSs: 0.203 ± 0.111; ITSSv:0.206 ± 0.098; R2* value:20.340 ± 5.572Hz; AFP: 1.73(1.33,2.99)ng/ml; PNI:49.150(45.825,51.775)) than that of the CSC group (ITSSs: 0.072 ± 0.019; ITSSv: 0.076 ± 0.030; R2* value: 13.233 ± 4.083Hz; AFP: 2.99(1.88,2.99)ng/ml; PNI: 50.775(48.563,54.050)) ( Conclusion: ITSSv and R2* values derived from ESWAN facilitate the quantitative differentiate between CA and CSC. The automated extraction of ITSSv is convenient and reliable, making it a promising candidate for clinical implementation.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.