ReviewCurrent opinion in infectious diseases2026
"O for KP": an evidence review on recentering HIV prevention and PrEP delivery for key populations and the underserved.
Review in Current opinion in infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
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Authors and funding
3 authors.
Funding
Abstract
purpose of reviewDespite the proven efficacy of preexposure prophylaxis (PrEP), global coverage remains far below targets, with the greatest gaps among key and underserved populations. This review is timely as it highlights how inequitable access undermines progress toward ending AIDS by 2030 and introduces the "O for KP" framework - a preferential option for key populations and the underserved . This equity-focused principle redefines program success by how well services reach and sustain those most structurally excluded. RECENT
findingsWe synthesized evidence on persistent barriers faced by men who have sex with men, transgender people, migrants, people who inject drugs, and others disproportionately affected by HIV. Effective strategies include community-led and peer-driven approaches, integration of gender-affirming and harm reduction services, digital and self-care innovations, task-sharing, and supportive policy reforms. Methods such as human-centred design, preference research, behavioural science frameworks, and implementation science tools have been critical in tailoring and scaling interventions. SUMMARY: Adopting an O for KP lens requires shifting beyond pilots and aggregate coverage metrics to approaches that centre the most underserved. Embedding community leadership, diversifying delivery models, and reforming restrictive policies are essential to maximize PrEP's impact and ensure progress toward global HIV prevention goals.
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