Evidence mapPaperPMID 41344918Full record

ArticleBMJ open respiratory research2025

Treatable moments for smoking cessation in asthma and COPD: a nationwide cohort study.

Delphine Vauterin, Adam Edward Lang, Kristiaan Proesmans, Maxim Grymonprez, Lies Lahousse

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Article in BMJ open respiratory research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Delphine VauterinDepartment of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Gent, Belgium.ORCID http://orcid.org/0000-0002-8932-476X
Adam Edward LangDepartment of Family Medicine and Population Health, Virginia Commonwealth University School of Medicine, Richmond, Virginia, USA.
Kristiaan ProesmansDepartment of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Gent, Belgium.
Maxim GrymonprezDepartment of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Gent, Belgium.
Lies LahousseDepartment of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Gent, Belgium lies.lahousse@ugent.be.ORCID http://orcid.org/0000-0002-3494-4363

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSmoking cessation has proven to be the most effective non-pharmacological intervention to tackle poor outcomes in airway diseases. However, there is limited understanding of teachable/treatable moments (specific times when individuals may be particularly open to behavioural change) to support smoking cessation in patients with asthma or chronic obstructive pulmonary disease (COPD). Therefore, we aimed to investigate which health events could create treatable moments for nicotine dependence in these patients.

methodsPatients aged ≥18 years, chronically using medication for obstructive lung diseases between 2017 and 2022 and currently smoking tobacco were identified in Belgian nationwide administrative health data. The impact of potential triggering events on evidence-based cessation attempts (reimbursed tobacco counselling or cessation medication) was investigated by multivariable Cox proportional hazard models. Additional analyses stratified by care setting where cessation was attempted (inpatient vs outpatient), restricted to a first attempt, incident triggering events only and stratified by hospital label (no label, asthma or COPD separately) were conducted.

resultsAmong 94 788 chronic users of pulmonary medication (mean age 61.6 years, 49% female), 12 499 (13.2%) patients attempted smoking cessation. Severe exacerbations (adjusted HR (aHR) 1.82, 95% CI 1.73 to 1.90), use of antidepressants (aHR 1.70, 95% CI 1.64 to 1.76), smoking-related cancer (aHR 1.42, 95% CI 1.33 to 1.52), peripheral vascular disease (aHR 1.42, 95% CI 1.35 to 1.49), admission to critical care (aHR 1.42, 95% CI 1.35 to 1.49), spirometry testing (aHR 1.33, 95% CI 1.27 to 1.38), acute myocardial infarction (aHR 1.32, 95% CI 1.21 to 1.44) and stroke (aHR 1.28, 95% CI 1.18 to 1.38) were associated with a significantly increased likelihood of smoking cessation attempt by more than 25%. All additional analyses confirmed the main findings.

conclusionsIn this nationwide cohort study, we have identified significant treatable moments for smoking cessation beyond established triggering events (eg, stroke and acute myocardial infarction). Exacerbations and spirometry testing were associated with a significantly increased chance of a smoking cessation attempt.

Indexed as

AsthmaPulmonary Disease, Chronic ObstructiveSmoking CessationTobacco Use DisorderAdultAgedBelgiumCohort StudiesFemaleHumansMaleMiddle AgedAsthmaAsthma EpidemiologyCOPD epidemiologyCOPD ExacerbationsPulmonary Disease, Chronic ObstructiveTobacco and the lung

Identifiers

PMID41344918
PMCPMC12684223

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.