Evidence map›Paper›PMID 41345429›Full record

ArticleScientific reports2025

Association of hearing loss with cardiovascular and mortality risk in the general population.

Omar Hahad, Julia Döge, Katharina Bahr-Hamm, Jasmin Ghaemi Kerahrodi, Katharina Geschke, Konstantin Kontohow-Beckers, Alexander K Schuster, Emilio Gianicolo, Karl J Lackner, Julia Weinmann-Menke and 4 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Omar HahadDepartment of Cardiology - Cardiology I, University Medical Center of the Johannes Gutenberg-University Mainz, Langenbeckstraße 1, 55131, Mainz, Germany. omar.hahad@unimedizin-mainz.de.
Julia DögeDepartment of Otorhinolaryngology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Katharina Bahr-HammDepartment of Otorhinolaryngology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Jasmin Ghaemi KerahrodiDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Katharina GeschkeDepartment of Psychiatry and Psychotherapy, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Konstantin Kontohow-BeckersPreventive Cardiology and Preventive Medicine, Department of Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Alexander K SchusterDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Emilio GianicoloInstitute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Karl J LacknerInstitute of Clinical Chemistry and Laboratory Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Julia Weinmann-MenkeDepartment of Nephrology, I. Department of Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Philipp LurzDepartment of Cardiology - Cardiology I, University Medical Center of the Johannes Gutenberg-University Mainz, Langenbeckstraße 1, 55131, Mainz, Germany.
Stavros KonstantinidesCenter for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Philipp S WildGerman Center for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Mainz, Germany.
Berit HackenbergDepartment of Otorhinolaryngology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hearing loss affects over 1.5 billion individuals worldwide and is associated with significant challenges, including social isolation and cognitive decline. Emerging evidence suggests a link between hearing loss and cardiovascular diseases. Comprehensive epidemiological studies exploring these associations remain limited. Using data from the Gutenberg Health Study, a population-based cohort of 15,010 participants aged 35-74 years at baseline, we investigated the relationship between hearing loss, cardiovascular diseases and risk factors, and all-cause mortality. Participants underwent extensive audiometric assessments and clinical evaluations. Logistic regression and Cox proportional hazards models were applied to determine associations between hearing loss, cardiovascular health, and mortality, adjusting for potential confounders. Among the 8886 participants with complete hearing data, 35.1% exhibited some degree of hearing loss. Crude models revealed significant associations between hearing loss and various cardiovascular diseases and risk factors. However, these associations lost significance after adjustments for confounders, except for diabetes (adjusted odds ratio 1.24, 95% confidence interval (CI) 1.01-1.51). Hearing loss coincided with higher mortality in unadjusted analyses (hazard ratio 5.64, 95% CI 4.24-7.49), but this relationship disappeared after full adjustment. Hearing loss may serve as an early marker of systemic vascular dysfunction, particularly in diabetes, rather than an independent predictor of cardiovascular disease or mortality. It needs to be determined whether incorporating auditory health into broader cardiovascular assessments could improve early detection and prevention strategies.

Indexed as

Cardiovascular DiseasesHearing LossAdultAgedFemaleHumansMaleMiddle AgedProportional Hazards ModelsRisk FactorsCardiovascular diseaseDiabetesEpidemiologyHearing lossMortality

Identifiers

PMID41345429
PMCPMC12680764

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.