Evidence map›Paper›PMID 41345563›Full record

ArticleBMC gastroenterology2025

The effects of family-based Helicobacter pylori infection control and management strategies in Southwest China households: a two-year retrospective cohort study.

Hengqi Liu, Hanning Liu, Ling Fan, Yuntong Lan, Ping Chen, Ping He, Cheng Huang, Sai Gu, Haofeng Li, Qing Shi and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hengqi Liu *Department of Gastroenterology and Hepatology, The Army Medical Center of People's Liberation Army, Chongqing, 400042, China.
Hanning Liu *Department of Gastroenterology and Hepatology, The Army Medical Center of People's Liberation Army, Chongqing, 400042, China.
Ling FanDepartment of Gastroenterology and Hepatology, The Army Medical Center of People's Liberation Army, Chongqing, 400042, China.
Yuntong LanDepartment of Gastroenterology and Hepatology, Chongqing Hospital of Jiangsu Province Hospital, Chongqing, China.
Ping ChenDepartment of Gastroenterology and Hepatology, Chongqing University Three Gorges Hospital, Chongqing, China.
Ping HeDepartment of Gastroenterology and Hepatology, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Cheng HuangDepartment of Gastroenterology and Hepatology, Chonggang General Hospital, Chongqing, China.
Sai GuDepartment of Gastroenterology and Hepatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Haofeng LiDepartment of Gastroenterology and Hepatology, The Army Medical Center of People's Liberation Army, Chongqing, 400042, China.
Qing ShiDepartment of Gastroenterology and Hepatology, The Army Medical Center of People's Liberation Army, Chongqing, 400042, China.
Chunhui LanDepartment of Gastroenterology and Hepatology, The Army Medical Center of People's Liberation Army, Chongqing, 400042, China. lanchunhui@tmmu.edu.cn.
Yan GuoDepartment of Gastroenterology and Hepatology, The Army Medical Center of People's Liberation Army, Chongqing, 400042, China. guoyan1112@tmmu.edu.cn.

Funding

Army Medical Center Artificial Intelligence + Medical Research Project ZXAIYB009Clinical Medical Innovation Competency Development Program of the Army Medical Center of People's Liberation Army 2019CXLCB003
6 · The paper itself

Abstract

backgroundThere is a lack of data on the effects of family-based Helicobacter pylori (H. pylori) infection control and management (FBCM) strategies in Southwest China. This study aimed to evaluate the two-year outcomes of these strategies in affected households.

methodsIndividuals who participated in a two-year H. pylori survey in Chongqing (China) were included in the study. Households where all H. pylori-infected members underwent eradication treatment were classified as group A, while those that did not follow whole family eradication therapy were designated as group B. The eradication rate, incidence of new infections, and changes in hygiene and living habits, were compared between the two groups.

resultsThis study included 472 cases from 171 families, including 296 in group A and 176 in group B. The eradication rate in group A was significantly higher than that in group B (89.39% vs. 70.45%, p = 0.003). The compliance (87.88% vs. 84.09%, p = 0.519) and timely reexamination rates (46.97% vs. 31.82%, p = 0.063) were similar between the two groups. Among H. pylori-infected cases, the endoscopy uptake rate in group A was significantly higher than that in group B (30.30% vs. 13.98%, p = 0.004). Group A exhibited significant hygiene improvements after 2 years, including reduced raw water drinking (5.74% vs. 2.36%, p = 0.037), decreased shared cup usage (27.70% vs. 9.46%, p < 0.001), and increased individual dining (6.08% vs. 16.22%, p < 0.001). Group B showed decreased shared plate usage (26.14% vs. 5.11%, p < 0.001) and increased plate disinfection rates (25.00% vs. 44.89%, p < 0.001).

conclusionThe FBCM strategy significantly improved H. pylori eradication rates and promoted healthier hygiene behaviors.

Indexed as

Helicobacter InfectionsHelicobacter pyloriAdultAnti-Bacterial AgentsChinaFamily CharacteristicsFemaleHumansHygieneIncidenceMaleMiddle AgedRetrospective StudiesAnti-Bacterial AgentsEpidemiologyFamily-based infection control and managementHelicobacter pylori

Identifiers

PMID41345563
PMCPMC12679750

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.