Evidence map›Paper›PMID 41345633›Full record

ArticleBMC public health2025

Exploring barriers to hypertension medication adherence among people living with HIV enrolled in the iHEART-SA trial: a theoretical domains framework qualitative study.

Wellington Maruma, E Oladimeji, A Nyatela, M Heine, S T Lalla-Edward, W D F Venter, K Klipstein-Grobusch

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wellington MarumaDepartment of Global Public Health and Bioethics, Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, PO Box 85500, Utrecht, 3508 GA, The Netherlands. T.W.Maruma@umcutrecht.nl.
E OladimejiFaculty of Health Sciences, University of the Witwatersrand, Ezintsha, Johannesburg, South Africa.
A NyatelaFaculty of Health Sciences, University of the Witwatersrand, Ezintsha, Johannesburg, South Africa.
M HeineDepartment of Global Public Health and Bioethics, Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, PO Box 85500, Utrecht, 3508 GA, The Netherlands.
S T Lalla-EdwardFaculty of Health Sciences, University of the Witwatersrand, Ezintsha, Johannesburg, South Africa.
W D F VenterFaculty of Health Sciences, University of the Witwatersrand, Ezintsha, Johannesburg, South Africa.
K Klipstein-GrobuschDepartment of Global Public Health and Bioethics, Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, PO Box 85500, Utrecht, 3508 GA, The Netherlands.

Funding

NHLBI NIH HHS UG3 HL156388NIH HHS UG3HL156388
6 · The paper itself

Abstract

backgroundHypertension significantly increases the risk of cardiovascular complications, posing a dual burden for people living with HIV (PLHIV) in Sub-Saharan Africa. This study explores the barriers and enablers of hypertension medication adherence among PLHIV attending three primary healthcare (PHC) facilities in Johannesburg, South Africa.

methodsA qualitative study design was employed, guided by the Theoretical Domains Framework (TDF). Data were collected through interviews and focus group discussions with a purposive sample of PLHIV and healthcare providers. Sessions were recorded, transcribed, de-identified, and analysed using inductive thematic analysis, with themes categorized using the TDF.

resultsNineteen participants (healthcare providers, n = 6; PLHIV, n = 13) identified four key themes influencing hypertension medication adherence: (1) delays in seeking hypertension care (2), gaps in hypertension-related knowledge among patients (3), the role of social support in encouraging adherence, and (4) limited integration of hypertension care services into HIV programs. Barriers included reliance on traditional medicine, high pill burden, socio-economic challenges, and long waiting times. Social support and targeted educational interventions were identified as facilitators to improve adherence.

conclusionAddressing barriers to hypertension medication adherence among PLHIV requires a multifaceted approach. Interventions focusing on improving health literacy, fostering social support, and integrating hypertension care into routine HIV services are essential for optimizing health outcomes.

Indexed as

Antihypertensive AgentsHIV InfectionsHypertensionMedication AdherenceAdultFemaleFocus GroupsHumansInterviews as TopicMaleMiddle AgedQualitative ResearchSocial SupportSouth AfricaAntihypertensive AgentsHIVHypertensionMedication adherencePrimary healthcareSouth africaTheoretical domains framework

Identifiers

PMID41345633
PMCPMC12797747

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.