Evidence mapPaperPMID 41345670Full record

ReviewJournal of translational medicine2025

Synergizing biomaterials and cellular molecular pathways: a new frontier in hair follicle generation.

Amir Bajouri, Nasser Aghdami, Mohammad Ali Nilforoushzadeh

Abstract readReview
In one paragraph

Review in Journal of translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Amir BajouriSkin and Stem Cell Research Center, Tehran University of Medical Sciences, P.O. Box: 1937957511, No.4, Maryam Dead End, South Andarzgo Blvd, Kamraniyeh, Tehran, Iran.
Nasser AghdamiDepartment of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, P.O. Box: 16635148, Hafez Alley Nr.2, Banihashem, Resalat, Tehran, Iran.
Mohammad Ali NilforoushzadehSkin and Stem Cell Research Center, Tehran University of Medical Sciences, P.O. Box: 1937957511, No.4, Maryam Dead End, South Andarzgo Blvd, Kamraniyeh, Tehran, Iran. nilforoosh@sina.tums.ac.ir.ORCID 0009-0004-1540-0557

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite significant advances in our understanding of hair follicle cycling and regeneration, creating fully functional hair follicles with active cycling capabilities remains a considerable challenge for clinical applications. This literature review aims to explore the molecular and cellular mechanisms that govern hair follicle development and cycling, highlighting key signaling pathways involved in these processes. We also discuss biomaterials and emerging regenerative strategies that show promise for biofabricating hair follicles. Specifically, we summarize current research on innovative techniques such as hair micropatterning models, hair follicle organoids, three-dimensional printing of microneedle arrays, microfollicle generation, and biofabrication technologies. This review emphasizes the necessity of a multifaceted approach that integrates stem cell research and tissue engineering technologies to optimize hair follicle regeneration and enhance therapeutic outcomes.

Indexed as

Biocompatible MaterialsHair FollicleSignal TransductionAnimalsHumansRegenerationStem CellsTissue EngineeringBiocompatible MaterialsHair follicleOrganoidsRegenerationRegenerative medicineStem cells

Identifiers

PMID41345670
PMCPMC12676848

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.