ArticleFrontiers in nutrition2025
Imbalanced nutrition and increased dietary inflammatory index in children with autism spectrum disorder: associations with neurodevelopmental disorders.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Selective Hematological Profiles in Drug-Naïve Early Autism: Clinical and Developmental Correlates.Biomedicines · 2026Article
- Eating Behaviors and Energy and Nutrient Intakes in Children with Autism Spectrum Disorder with and Without Sensory Integration Difficulties.Children (Basel, Switzerland) · 2026Article
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Authors and funding
9 authors.
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Abstract
Background: The incidence rate of autism spectrum disorders (ASDs) has been rising; this study aimed to explore the relationship between nutritional intake and neurodevelopment in children with ASDs. Methods: This study is a case-control cross-sectional comparison including 50 children with ASDs and 50 typically developing controls. A total of 500 children with neurodevelopmental disorders and 500 typically developing (TD) children were recruited based on clinical diagnosis to compare levels of inflammation. Among them, 50 children were diagnosed with ASDs based on DSM-5 criteria by experienced developmental behavioral pediatricians. A total of 50 typically developing children were matched with the 50 children with ASDs. Dietary surveys, Autism Diagnostic Observation Schedule (ADOS), and physical development evaluations were conducted on these 100 children. Results: The children's dietary inflammatory index (C-DII), systemic immune inflammatory index (SII), and systemic inflammatory response index (SIRI) in the ASD group were significantly higher compared to the TD group ( Conclusion: Children with autism spectrum disorders (ASD) displayed higher C-DII scores. The results of this study suggest that there may be a correlation between C-DII and the neurodevelopment of children with ASD, not causality. Inflammatory dietary patterns may represent a modifiable factor linked to neurodevelopmental outcomes.
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