ArticleFrontiers in medicine2025
Association of d-dimer levels with in-hospital death and multi-vessel coronary artery disease in patients with non-ST-segment elevation acute coronary syndrome.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: To determine the association of d-dimer levels with in-hospital death and coronary artery disease (CAD) in patients with non-ST-segment elevation acute coronary syndrome (NSTEACS). Methods: We retrospectively analyzed the data of 803 NSTEACS patients admitted to Beijing Anzhen Hospital between January 2022 and January 2024. Demographic, clinical, and laboratory data were compared between survivors (792 patients) and non-survivors (11 patients). Risk factors for in-hospital death were analyzed. The cutoff plasma d-dimer level was determined using the Youden index to predict in-hospital death in patients with NSTEACS, and the rates of in-hospital mortality and multi-vessel CAD (2-vessel + 3-vessel disease) were compared between patients with high (103 patients) and low d-dimer levels (700 patients). Results: D-dimer [odds ratio (OR): 1.003, Conclusion: The higher the d-dimer level in NSTEACS patients, the higher the risk of in-hospital death and the higher the probability of multi-vessel CAD. D-dimer levels were significantly associated with in-hospital death and multi-vessel CAD in NSTEACS patients.
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