Evidence map›Paper›PMID 41347052›Full record

Trial reportNeural plasticity2025

Brain-Wave Music: A Personalized Approach to Improving Anxiety Resistance.

Haohan Yang, Yan Li, Haoyu Bian, Chenxi Qiu, Xinjian Su, Jiaxian Chen, Roberto Rodriguez-Labrada, Jing Lu, Dezhong Yao

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Neural plasticity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Haohan YangYingcai Honors College, University of Electronic Science and Technology of China, Chengdu 611731, Sichuan, China.
Yan LiKey Lab for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 611731, Sichuan, China.
Haoyu BianKey Lab for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 611731, Sichuan, China.
Chenxi QiuKey Lab for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 611731, Sichuan, China.
Xinjian SuKey Lab for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 611731, Sichuan, China.
Jiaxian ChenKey Lab for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 611731, Sichuan, China.
Roberto Rodriguez-LabradaCuban Neuroscience Center, La Habana 11600, Cuba.
Jing LuKey Lab for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 611731, Sichuan, China.ORCID 0000-0002-3519-3055
Dezhong YaoKey Lab for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 611731, Sichuan, China.ORCID 0000-0002-8042-879X

Funding

China Manned Space Medical Experiment Project of CMSPNational Key R&D Program of ChinaNational Natural Science Foundation of China
6 · The paper itself

Abstract

Introduction: Music has long been recognized for its potential to modulate anxiety resistance at the population level. However, there is a lack of an auditory method that performs general and effective in enhancing anxiety resistance. Here we investigate the impact of a specific music that directly reflects brain activity (brain-wave music [BWM]) on anxiety resistance and its underlying neural mechanisms. Method: A two-phase experimental protocol was designed utilizing the ToS anxiety induction paradigm to examine the efficacy of BWM in enhancing anxiety resistance. In Phase 1, resting-state EEG recordings were initially collected from 70 participants, followed by a standardized anxiety induction procedure involving auditory cues, to validate the effectiveness of the anxiety induction paradigm and establish baseline anxiety resistance for each participant. Phase 2, designed based on Phase 1 and conducted 24 h later, further investigated the neural mechanisms underlying anxiety regulation through brain-music intervention. Participants were randomly allocated into three groups: BWM ( Results: Compared to Phase 1 resting-state baseline, the BWM group exhibited significantly reduced SAI scores in Phase 2, accompanied by enhanced prefrontal theta oscillations and functional connectivity between the prefrontal cortex, parietal lobe, and auditory cortex. No significant changes were observed in the other groups. Discussion: These findings suggest that BWM effectively promotes anxiety resistance by facilitating network connectivity between the prefrontal and multisensory regions. Moreover, this study highlights BWM as a novel and promising method for emotional regulation.

Indexed as

AnxietyBrainBrain WavesMusicMusic TherapyAcoustic StimulationAdultAuditory PerceptionElectroencephalographyFemaleHumansMaleYoung AdultanxietyEEGmusic

Identifiers

PMID41347052
PMCPMC12674876

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.