Evidence map›Paper›PMID 41347235›Full record

ArticleFrontiers in microbiology2025

Metabolomic profiling of indigenous lactic acid bacteria reveals functional traits shaping the flavor and bioactivity of Ecuadorian coffee.

Victor Cifuentes, Ioana C Marinas, George Cătălin Marinescu, Roua Gabriela Popescu, Mariana C Chifiriuc, Gabriela N Tenea

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Victor CifuentesBiofood and Nutraceutics Research and Development Group, Faculty of Engineering in Agricultural and Environmental Sciences, Universidad Técnica del Norte, Ibarra, Ecuador.
Ioana C MarinasResearch Institute of the University of Bucharest-ICUB, University of Bucharest, Bucharest, Romania.
George Cătălin MarinescuIndependent Research Association, Bucharest, Romania.
Roua Gabriela PopescuIndependent Research Association, Bucharest, Romania.
Mariana C ChifiriucResearch Institute of the University of Bucharest-ICUB, University of Bucharest, Bucharest, Romania.
Gabriela N TeneaBiofood and Nutraceutics Research and Development Group, Faculty of Engineering in Agricultural and Environmental Sciences, Universidad Técnica del Norte, Ibarra, Ecuador.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Microbial fermentation by lactic acid bacteria (LAB) significantly influences the flavor, quality, and functional attributes of coffee. However, the specific metabolic outputs and roles of LAB native strains to distinct Methods: Metabolite profiling was performed using capillary liquid chromatography tandem mass spectrometry (LC-MS/MS) with a SWATH-based data-independent acquisition (DIA) strategy in positive electrospray ionization (ESI+) mode, enabling detection of metabolites associated with flavor development, stress response, and antimicrobial potential. Functional group analysis via attenuated total reflectance Fourier transforms infrared (ATR-FTIR) spectroscopy provided insights into structural and biochemical changes, including protein, carbohydrate, and lipid modifications during LAB activity. Total polyphenol content (TPC) and total flavonoid content (TFC) were quantified to assess nutritional and antioxidant shifts. Results: Strain-specific metabolic signatures were identified. Conclusion: This study demonstrates the functional diversity of indigenous LAB strains from

Indexed as

Coffea arabicaharmanelactic acid bacteriaLC-MS/MS untargeted metabolomicsmetabolitespolyphenols

Identifiers

PMID41347235
PMCPMC12672526

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.