Evidence map›Paper›PMID 41347238›Full record

ArticleFrontiers in microbiology2025

Strain-specific tropism and transcriptional responses of enterovirus D68 infection in human spinal cord organoids.

Nathânia Dábilla, Sarah Maya, Colton McNinch, Taylor Eddens, Patrick T Dolan, Megan Culler Freeman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Organoids for disease modeling and treatment: state-of-the-art.Experimental hematology & oncology · 2026
    Review
  6. Review
  7. Review
  8. Human Assembloid Model of Emergent Neurotropic Enteroviruses.bioRxiv : the preprint server for biology · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Nathânia Dábilla *Quantitative Virology and Evolution Unit, Laboratory of Viral Diseases, NIH-NIAID Division of Intramural Research, Bethesda, MD, United States.
Sarah Maya *Department of Pediatrics, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
Colton McNinchBioinformatics and Computational Bioscience Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, United States.
Taylor EddensDepartment of Pediatrics, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
Patrick T DolanQuantitative Virology and Evolution Unit, Laboratory of Viral Diseases, NIH-NIAID Division of Intramural Research, Bethesda, MD, United States.
Megan Culler FreemanDepartment of Pediatrics, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.

Funding

Virus evolution and host responses in positive-sense RNA virusesZIAAI001360 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI DOLAN, PATRICK · 2022 to 2025
$7.4M
Investigation of enterovirus D68 pathogenesis in the human spinal cordK08AI171177 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Megan Culler Freeman · 2022 to 2026
$836k
Intramural NIH HHS ZIA AI001360NIAID NIH HHS K08 AI171177
6 · The paper itself

Abstract

The mechanisms by which

Indexed as

enterovirusEV-D68organoidssingle-cell RNA sequencingspinal cordsystems biology

Identifiers

PMID41347238
PMCPMC12672529

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.