Evidence map›Paper›PMID 41347775›Full record

ArticleeLife2025

Characterisation of cell-scale signalling by the core planar polarity pathway during

Alexandre Carayon, Helen Strutt, David Strutt

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alexandre CarayonSchool of Biosciences, University of Sheffield, Sheffield, United Kingdom.ORCID https://orcid.org/0000-0003-4440-7112
Helen StruttSchool of Biosciences, University of Sheffield, Sheffield, United Kingdom.ORCID https://orcid.org/0000-0003-4365-2271
David StruttSchool of Biosciences, University of Sheffield, Sheffield, United Kingdom.ORCID https://orcid.org/0000-0001-8185-4515

Funding

Wellcome TrustWellcome Trust 10.35802/210630Wellcome Trust 10.35802/305132
6 · The paper itself

Abstract

In developing epithelia, cells become planar polarised through asymmetric localisation of the core planar polarity proteins to opposite cell membranes, where they form stable intercellular complexes. Current models differ regarding the signalling mechanisms required for core protein polarisation. Here, we investigate the existence of cell-intrinsic cell-scale signalling in vivo in the

Indexed as

Cell PolarityDrosophila melanogasterSignal TransductionWings, AnimalAnimalsDrosophila ProteinsPupaDrosophila Proteinscell biologydevelopmental biologyD. melanogasterDrosophila wingfrizzledmicrotubulesPCPplanar cell polarityplanar polaritysignalling

Identifiers

PMID41347775
PMCPMC12680375

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.