Evidence map›Paper›PMID 41347783›Full record

ArticleMicrobiology spectrum2026

The expansion of culturable opportunistic pathogens and antibiotic resistance in mouse gut following antibiotic exposure.

Bianfang Wang, Jian Zhang, Yuqing Sun, Xin Wei, Wenli Lai, Tingting Guo, Chengzhang Fu, Youming Zhang, Hai Xu, Ling Li and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bianfang Wang *State Key Laboratory of Microbial Technology, School of Life Sciences, Shandong University, Qingdao, Shandong, China.
Jian Zhang *State Key Laboratory of Microbial Technology, School of Life Sciences, Shandong University, Qingdao, Shandong, China.
Yuqing SunState Key Laboratory of Microbial Technology, School of Life Sciences, Shandong University, Qingdao, Shandong, China.
Xin WeiState Key Laboratory of Microbial Technology, School of Life Sciences, Shandong University, Qingdao, Shandong, China.
Wenli LaiState Key Laboratory of Microbial Technology, School of Life Sciences, Shandong University, Qingdao, Shandong, China.
Tingting GuoState Key Laboratory of Microbial Technology, School of Life Sciences, Shandong University, Qingdao, Shandong, China.
Chengzhang FuWorkgroup Genome Mining for Secondary Metabolites, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research, Saarland University, Saarbrücken, Germany.
Youming ZhangState Key Laboratory of Microbial Technology, School of Life Sciences, Shandong University, Qingdao, Shandong, China.
Hai XuState Key Laboratory of Microbial Technology, School of Life Sciences, Shandong University, Qingdao, Shandong, China.ORCID 0000-0001-8710-3026
Ling LiState Key Laboratory of Microbial Technology, School of Life Sciences, Shandong University, Qingdao, Shandong, China.ORCID 0000-0002-8390-8975
Mingyu WangState Key Laboratory of Microbial Technology, School of Life Sciences, Shandong University, Qingdao, Shandong, China.ORCID 0000-0003-1215-9556

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotics significantly change gut microbiota, leading to dysbiosis and changes in bacterial community composition, which further results in a series of dysfunctions with severe health consequences. This work employed both culture-dependent and -independent methods to examine antibiotic-induced changes in gut microbiota at higher resolution using mouse models. By following bacterial changes and antibiotic resistance daily before antibiotic exposure, after antibiotic exposure, and during recovery, several significant novel findings were made. Ampicillin (AMP) and imipenem (IPM) treatment led to an acute, exponential, but temporary bloom in absolute abundances of live opportunistic pathogens Enterobacteriaceae and

Indexed as

Anti-Bacterial AgentsBacteriaDrug Resistance, BacterialGastrointestinal MicrobiomeGastrointestinal TractAmpicillinAnimalsDysbiosisEnterobacteriaceaeEnterococcusFemaleImipenemMiceMice, Inbred C57BLAmpicillinAnti-Bacterial AgentsImipenemampicillinculturing-dependent analysisEnterobacteriaceaeEnterococcusgut microbiotaimipenemLactobacillus

Identifiers

PMID41347783
PMCPMC12772332

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.