Evidence map›Paper›PMID 41347918›Full record

ArticleRadiology. Imaging cancer2026

Arterial-Washout Temporal Profiling in CEUS LI-RADS: A Diagnostic Algorithm for Reducing Hepatocellular Carcinoma Misclassification.

Yang Wang, Zhixian Zhu, Mengjiao Zhu, Size Wu

Abstract read
In one paragraph

Article in Radiology. Imaging cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Yang WangDepartment of Ultrasound, The First Affiliated Hospital of Hainan Medical University, No. 31 Longhua Road, Haikou 570102, China.ORCID 0000-0002-3465-6468
Zhixian ZhuDepartment of Ultrasound, The First Affiliated Hospital of Hainan Medical University, No. 31 Longhua Road, Haikou 570102, China.ORCID 0009-0003-1730-0974
Mengjiao ZhuDepartment of Ultrasound, The First Affiliated Hospital of Hainan Medical University, No. 31 Longhua Road, Haikou 570102, China.
Size WuDepartment of Ultrasound, The First Affiliated Hospital of Hainan Medical University, No. 31 Longhua Road, Haikou 570102, China.ORCID 0000-0002-1086-764X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose To determine whether combining the arterial phase onset time to washout onset time interval (AWTI) with washout onset time improves the accuracy of contrast-enhanced US (CEUS) Liver Imaging Reporting and Data System (LI-RADS) and reduces the incidence of hepatocellular carcinoma (HCC) being misclassified as LR-M. Materials and Methods CEUS and clinical data from patients with focal liver lesions (FLLs), collected between January 2019 and October 2024, were retrospectively analyzed. The AWTI was calculated for all FLLs with washout < 60 seconds. A revised classification was proposed:

Indexed as

Carcinoma, HepatocellularContrast MediaLiver NeoplasmsAgedAlgorithmsFemaleHumansMaleMiddle AgedRetrospective StudiesUltrasonographyContrast MediaAbdomen/GIClassificationContrast Agents-IntravenousContrast-enhanced UltrasoundDiagnosisEfficacy StudiesHepatocellular CarcinomaLiverLiver Imaging Reporting and Data SystemReconstruction AlgorithmsUltrasoundUltrasound-ContrastWashout Time

Identifiers

PMID41347918
PMCPMC12862477

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.