Evidence map›Paper›PMID 41348322›Full record

ArticleEuropean journal of applied physiology2026

Adaptation of mtDNA content to endurance training, a cross-sectional study and an endurance training intervention.

Isabel María Sánchez Lorente, Thomas Yvert, Tamara Iturriaga, Lara Sanchez-Barroso, Mar Larrosa, Margarita Pérez-Ruiz, Catalina Santiago-Dorrego

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Isabel María Sánchez Lorente *ESBIDA Research Group, Department of Sport Sciences, Faculty of Medicine, Health and Sports, Universidad Europea de Madrid, Madrid, Spain.
Thomas Yvert *ImFINE Research Group, Department of Health and Human Performance, Universidad Politécnica de Madrid, Madrid, Spain. thomas.yvert@upm.es.ORCID http://orcid.org/0000-0002-9451-9799
Tamara IturriagaESBIDA Research Group, Department of Sport Sciences, Faculty of Medicine, Health and Sports, Universidad Europea de Madrid, Madrid, Spain.ORCID http://orcid.org/0000-0002-1073-7298
Lara Sanchez-BarrosoDepartment of Nursing, Facultad de Enfermería, Fisioterapia y Podología, Universidad Complutense de Madrid, Madrid, Spain.ORCID http://orcid.org/0000-0002-7042-578X
Mar LarrosaDepartment of Nutrition and Food Science, Faculty of Pharmacy, Universidad Complutense de Madrid, Madrid, Spain.ORCID http://orcid.org/0000-0002-8863-4686
Margarita Pérez-RuizImFINE Research Group, Department of Health and Human Performance, Universidad Politécnica de Madrid, Madrid, Spain.ORCID http://orcid.org/0000-0001-7240-2082
Catalina Santiago-DorregoESBIDA Research Group, Department of Rehabilitation, Faculty of Medicine, Health and Sports, Universidad Europea de Madrid, Madrid, Spain.ORCID http://orcid.org/0000-0003-3852-8217

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMaximal oxygen uptake (VO

objectiveThis study aimed to compare VO

methodsWe conducted a cross-sectional study with 20 highly trained runners and 20 nontrained healthy subjects. Then, we implemented a 6-week HIIT training programme for the nontrained group, comparing their VO

resultsThe cross-sectional part showed that highly trained runners had significantly higher mtDNA copy numbers than nontrained subjects (p = 0.046; d = 0.652; 95% CI: [0.01, 1.28]; [medium-large effect]); further, we observed a significant positive correlation between mtDNA copy number and VO

conclusionThese findings align with previous research, indicating that mtDNA copy number correlates with VO

Indexed as

Adaptation, PhysiologicalDNA, MitochondrialEndurance TrainingPhysical EnduranceAdultCross-Sectional StudiesHigh-Intensity Interval TrainingHumansLeukocytesMaleOxygen ConsumptionRunningDNA, MitochondrialLong HIITMitochondrial biogenesismtDNA copy numberRunningTreadmill training

Identifiers

PMID41348322
PMCPMC13171954

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.