Evidence map›Paper›PMID 41348483›Full record

ReviewKidney3602026

Mechanisms of Podocyte Injury in Kidney Allografts.

Gabriel C Barsotti, Madhav C Menon, Abhijit Naik, Arundati Rao

Abstract readReview
In one paragraph

Review in Kidney360, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gabriel C BarsottiDivision of Internal Medicine, Section of Nephrology, Yale University School of Medicine, New Haven, Connecticut.ORCID 0009-0006-1753-6380
Madhav C MenonDivision of Internal Medicine, Section of Nephrology, Yale University School of Medicine, New Haven, Connecticut.ORCID 0000-0002-9567-4299
Abhijit NaikDivision of Nephrology, Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, Michigan.ORCID 0000-0003-1602-9425
Arundati RaoDivision of Internal Medicine, Section of Nephrology, Yale University School of Medicine, New Haven, Connecticut.ORCID 0000-0003-0122-7816

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long-term kidney allograft survival remains an important clinical challenge. Although immune-mediated injury, particularly antibody mediated rejection, is associated with long-term graft loss, nonimmune mechanisms also drive chronic allograft failure. Podocytes are essential components of the glomerular filtration barrier, and their injury in the transplant setting may accelerate graft loss. In this review, we will discuss mechanisms of podocyte injury contributing to chronic graft failure including immune injury and nonimmune mechanisms such as immunosuppressive drug exposure and transplant-specific biomechanical changes.

Indexed as

Graft RejectionKidney TransplantationPodocytesAllograftsAnimalsGraft SurvivalHumansImmunosuppressive AgentsImmunosuppressive Agentschronic allograft failurechronic GNglomerular hyperfiltrationkidney transplantationpodocyteproteinuriatransplantationtransplant outcomes

Identifiers

PMID41348483
PMCPMC13337194

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.