Evidence map›Paper›PMID 41348646›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2026

Quantitative proteomics links mitochondrial dysfunction to metabolic changes and epithelial differentiation defects in hyperoxia-exposed neonatal airway cells.

Abhrajit Ganguly, Cynthia M Carter, Aristides Rivera Negron, Hua Zhong, Alvaro Moreira, Matthew S Walters, Lynette K Rogers, Y S Prakash, Trent E Tipple, Arlan Richardson

Abstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Abhrajit GangulySection of Neonatal-Perinatal Medicine, Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States.ORCID 0000-0003-1937-243X
Cynthia M CarterSection of Neonatal-Perinatal Medicine, Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States.
Aristides Rivera NegronSection of Neonatal-Perinatal Medicine, Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States.
Hua ZhongSection of Neonatal-Perinatal Medicine, Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States.
Alvaro MoreiraDivision of Neonatal Perinatal Medicine, Department of Pediatrics, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States.ORCID 0000-0003-3455-6608
Matthew S WaltersSection of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States.ORCID 0000-0003-0010-8444
Lynette K RogersSection of Neonatal-Perinatal Medicine, Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States.
Y S PrakashDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, United States.ORCID 0000-0002-2968-224X
Trent E TippleSection of Neonatal-Perinatal Medicine, Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States.ORCID 0000-0002-5156-4282
Arlan RichardsonDepartment of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States.

Funding

Tracking and Evaluation CoreU54GM104938 · NIGMS · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI JUDITH A JAMES · 2013 to 2026
$68.2M
Supplement for Google cloud build-outR24GM137786 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI Alan Tackett · 2020 to 2026
$15.4M
BLRD VA IK6 BX005238NIGMS NIH HHS R24 GM137786NIGMS NIH HHS U54 GM104938Pilot Award from Oklahoma Shared Clinical and Translational Resources (OSCTR)Presbyterian Health Foundation (PHF)U.S. Department of Veterans Affairs (VA) 1IK6BX005238Voucer Award from IDeA National Resource for Quantitative Proteomics
6 · The paper itself

Abstract

Newborn infants, especially those born preterm, often require supplemental oxygen (O

Indexed as

Cell DifferentiationEpithelial CellsHyperoxiaMitochondriaProteomicsRespiratory MucosaBronchopulmonary DysplasiaCells, CulturedHumansInfant, NewbornTracheabronchopulmonary dysplasiahyperoxiamitochondrial dysfunctionneonatal airway epitheliumquantitative proteomics

Identifiers

PMID41348646
PMCPMC12928458

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.